Polymyositis, dematomyositis: overlap syndromes with connective tissue diseases and malignancies

Polimiozitis i dermatomiozitis su često pridruženi autoimunim bolestima što je usko povezano sa specifičnim autoprotutijelima. Klinička slika ovih miozitisa je blaga naspram kliničke slike miozitisa povezanih s malignom bolešću. Plućne komplikacije su najčešći uzrok smrti kod preklapanja s autoimunim bolestima. Infekcije, kardiovaskularne komplikacije i pridružena maligna bolest razlog su povećanog mortaliteta.Polymyositis and Dermatomyositis are often connected with autoimmune diseases and are closely linked with specific autoantibodies. Clinical manifestations are mild in correlation with clinical picture of myositis related to malignancy. Pulmonary complications are main cause of mortality in overlap syndromes with autoimmune diseases. Infection, cardiovascular complications and underlying malignancy provide greater mortality risk