Microbiological analyses of the dental plaque in subjects with chronic renal failure

Grupi od 120 ispitanika (50 kroničnih bubrežnih bolesnika - Dg. Pyelonephritis ehr., 50 uremičara, 20 ispitanika kontrolne grupe) određena je mikrobiološka flora dentobakterijskog plaka sa glatkih ploha zuba. Identifikacija gram pozitivnih bakterija vršila se po Cowan-Steel- u, a gram negativnih bakterija po Edwards-Ewingu. Ustanovljeno je da u sve tri grupe među mikroflorom dentobakterijskog plaka dominiraju streptokoki, a među njima je najbrojniji Streptococcus mitis. Najveći postotak Streptococcus mutansa u odnosu na sve tri grupe nađen je kod kroničnih bubrežnih bolesnika (20%), dok je Streptococcus mitis u najvećem postotku izoliran kod uremičara (61,1%). Uremičari također imaju najveći postotak Candida. Kako je kod uremičara streptokokna flora bila više jednoobrazna to se može smatrati posljedicom aktivnosti amonijaka, odnosno promjeni u pH i visokoj osjetljivosti mikroorganizama na takove promjene.In a group of 120 examinees (50 patients with chronic kidney disease — Dg. Pyelonephritis chr., 50 with uremia and 20 control subjects) the microbiologic flora of the dental plaque on smooth tooth surfaces has been determined. Gram-positive bacteria were identified according to the method of Cowan and Steel and gram-negative bacteria according to Edwards and Ewing. In all three groups, streptococci were dominant in the microflora of the dentobacterial plaque, and among the streptococci Streptococcus mitis was the most numerous. The highest percentage of Streptococcus mutans was found in the group of patients with chronic renal disease (20%), while Streptococcus mitis was isolated in the highest percentage in uremic subjects (61.10/o). The uremics also had the highest percentage of Candida. The uniformity of the streptococcal flora in the uremic patients could be ascribed to the action of ammonia, i.e. to a change in pH and the high sensitivity of microorganisms to such changes