We report here the synthesis of a series of (aryltriazolyl)methylaziridines 1 and their evaluation as selective inhibitors of MMP-2.[2] They constitute a novel class of hydroxamic acid-free matrix metalloproteinase inhibitors
A number of matrix metalloproteinases (MMPs) are important medicinal targets for conditions ranging ...
In an effort to develop potent inhibitors of matrix metalloproteinases (MMPs), a bioinorganic approa...
A number of matrix metalloproteinases (MMPs) are important medicinal targets for conditions ranging ...
A series of (aryltriazolyl)methylaziridines were synthesized and evaluated as selective inhibitors o...
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that are responsible for cleavage...
Matrix metalloproteinases (MMPs) are an important family of zinc-containing enzymes with a central r...
Matrix metalloproteinases (MMPs) are an important family of zinc-containing enzymes with a central r...
The matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases involved in the d...
Matrix metalloproteinases (MMPs) are a large family of zinc-dependent endoproteases known to exert m...
Starting from the observation that the CbzNH(CH2)2 side chain of the potent MMP-2/MMP-14 inhibitor, ...
A novel matrix metalloproteinase-2 (MMP-2) inhibitor JaZ-30, which belongs to the class of C(2)-mono...
The synthesis of trifluoromethyl (Tfm) analogs of known nanomolar matrix metalloproteinases (MMPs) i...
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases, which degrade most o...
A new class of potent matrix metalloproteinase (MMP) inhibitors designed by structure-based optimiza...
Matrix metalloproteinases (MMPs) are key signaling modulators in the tumor microenvironment. Among M...
A number of matrix metalloproteinases (MMPs) are important medicinal targets for conditions ranging ...
In an effort to develop potent inhibitors of matrix metalloproteinases (MMPs), a bioinorganic approa...
A number of matrix metalloproteinases (MMPs) are important medicinal targets for conditions ranging ...
A series of (aryltriazolyl)methylaziridines were synthesized and evaluated as selective inhibitors o...
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that are responsible for cleavage...
Matrix metalloproteinases (MMPs) are an important family of zinc-containing enzymes with a central r...
Matrix metalloproteinases (MMPs) are an important family of zinc-containing enzymes with a central r...
The matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases involved in the d...
Matrix metalloproteinases (MMPs) are a large family of zinc-dependent endoproteases known to exert m...
Starting from the observation that the CbzNH(CH2)2 side chain of the potent MMP-2/MMP-14 inhibitor, ...
A novel matrix metalloproteinase-2 (MMP-2) inhibitor JaZ-30, which belongs to the class of C(2)-mono...
The synthesis of trifluoromethyl (Tfm) analogs of known nanomolar matrix metalloproteinases (MMPs) i...
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases, which degrade most o...
A new class of potent matrix metalloproteinase (MMP) inhibitors designed by structure-based optimiza...
Matrix metalloproteinases (MMPs) are key signaling modulators in the tumor microenvironment. Among M...
A number of matrix metalloproteinases (MMPs) are important medicinal targets for conditions ranging ...
In an effort to develop potent inhibitors of matrix metalloproteinases (MMPs), a bioinorganic approa...
A number of matrix metalloproteinases (MMPs) are important medicinal targets for conditions ranging ...