In this Editorial some of the global outlooks of Library and Information Science are discussed. After contextualizing the discipline within the cultural changes that have occurred in the Social Sciences before the advent of the virtual world, the author points out the characteristics of these emerging paradigms: The constant migration of media, the links between Library and Museum Studies, the articulation between the artificial and the natural language, the deterritorialization of the information and its users, the challenge of building a librarian profession with its own identity framed in global and transnational processes of information, among other perspectives