The usual course of infection by Plasmodium falciparum among adults who lack a history of exposure to endemic malaria is fulminant. The infection in adults living with hyper- to holoendemic malaria is chronic and benign. Naturally acquired immunity to falciparum malaria is the basis of this difference. Confusion surrounds an essential question regarding this process: What is its rate of onset? Opinions vary because of disagreement over the relationships between exposure to infection, antigenic polymorphism and naturally acquired immunity. In this review, Kevin Baird discusses these relationships against a backdrop of host age as a determinant of naturally acquired immunity to falciparum malaria
The duration of untreated Plasmodium falciparum infections is a defining characteristic of the paras...
Age- and exposure-dependent immune responses during a malaria episode may be key to understanding th...
Fundamental gaps remain in our understanding of how immunity to malaria develops. We used detailed c...
The usual course of infection by Plasmodium falciparum among adults who lack a history of exposure t...
Naturally acquired immunity to Plasmodium falciparum may be linked to key features of the immune sys...
Naturally acquired immunity to Plasmodium falciparum may be linked to key features of the immune sys...
<div><p>Severe malaria occurs predominantly in young children and immunity to clinical disease is as...
BACKGROUND: Natural immunity to Plasmodium falciparum has been widely studied, but its effects on pa...
Background: The rate of acquisition of naturally acquired immunity (NAI) against malaria predominant...
The rate of acquisition of naturally acquired immunity (NAI) against malaria predominantly depends o...
Naturally acquired immunity to falciparum malaria protects millions of people routinely exposed to P...
BACKGROUND: The rate of acquisition of naturally acquired immunity (NAI) against malaria predominant...
<div><h3>Background</h3><p>Natural immunity to <em>Plasmodium falciparum</em> has been widely studie...
Severe malaria occurs predominantly in young children and immunity to clinical disease is associated...
Naturally acquired immunity to falciparum malaria protects millions of people routinely exposed to P...
The duration of untreated Plasmodium falciparum infections is a defining characteristic of the paras...
Age- and exposure-dependent immune responses during a malaria episode may be key to understanding th...
Fundamental gaps remain in our understanding of how immunity to malaria develops. We used detailed c...
The usual course of infection by Plasmodium falciparum among adults who lack a history of exposure t...
Naturally acquired immunity to Plasmodium falciparum may be linked to key features of the immune sys...
Naturally acquired immunity to Plasmodium falciparum may be linked to key features of the immune sys...
<div><p>Severe malaria occurs predominantly in young children and immunity to clinical disease is as...
BACKGROUND: Natural immunity to Plasmodium falciparum has been widely studied, but its effects on pa...
Background: The rate of acquisition of naturally acquired immunity (NAI) against malaria predominant...
The rate of acquisition of naturally acquired immunity (NAI) against malaria predominantly depends o...
Naturally acquired immunity to falciparum malaria protects millions of people routinely exposed to P...
BACKGROUND: The rate of acquisition of naturally acquired immunity (NAI) against malaria predominant...
<div><h3>Background</h3><p>Natural immunity to <em>Plasmodium falciparum</em> has been widely studie...
Severe malaria occurs predominantly in young children and immunity to clinical disease is associated...
Naturally acquired immunity to falciparum malaria protects millions of people routinely exposed to P...
The duration of untreated Plasmodium falciparum infections is a defining characteristic of the paras...
Age- and exposure-dependent immune responses during a malaria episode may be key to understanding th...
Fundamental gaps remain in our understanding of how immunity to malaria develops. We used detailed c...