Paper Disk Columns in Glass Chromatographic Tubes

The use of filter paper in selective adsorption experiments, probably first described by Schonbein (1), has become a powerful tool in research, especially since the studies of Consden, Gordon, and Martin (2). Although in most modifications of paper chromatography only very small amounts of material can be resolved, Mitchell and his colleagues must be credited with preparative applications; recently these authors carried out successful enzyme separations in their chromatopile (3, 4)