Correlation of 6-18F-fluoro-L-dopa PET uptake with proliferation and tumor grade in newly diagnosed and recurrent gliomas
- Fueger, Barbara J
- Czernin, Johannes
- Cloughesy, Timothy
- Silverman, Daniel H
- Geist, Cheri L
- Walter, Martin A
- Schiepers, Christiaan
- Nghiemphu, Phioanh
- Lai, Albert
- Phelps, Michael E
- Chen, Wei
Publication date
January 2010
DOI Publisher
Society of Nuclear Medicine ISSN
0161-5505 Citation count (estimate)
85Abstract
6-(18)F-fluoro-l-dopa ((18)F-FDOPA) measured with PET as a biomarker of amino acid uptake has been investigated in brain tumor imaging. The aims of the current study were to determine whether the degree of (18)F-FDOPA uptake in brain tumors predicted tumor grade and was associated with tumor proliferative activity in newly diagnosed and recurrent gliomas
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