Migration of CXCR6+ activated/memory T-cells is stopped in response to hypoxia. T-cells (green) are seen migrating in a live MMTV-PyMT;ACTB-ECFP;CXCR6EGFP mouse. The same field is shown during normoxia (21% inhaled oxygen), hypoxia (7% inhaled oxygen) and re-established normoxia (21% oxygen). Cancer cells are labeled blue. From Egeblad et al. (2010) Dev. Cell, 18 884-901
The chemokine receptor CXCR4 plays a central role in organ-specific homing and tumor spreading and i...
Hypoxia within a tumor acts as a strong selective pressure that promotes angiogenesis, invasion, and...
The tumor microenvironment is characterized to be under severe conditions (nutrient shortage, low pH...
Migration of Foxp3+ regulatory T-lymphocytes is stopped in response to hypoxia. Regulatory T-lymphoc...
Migration of CXCR6+ activated/memory T-cells in the tumor microenvironment. CXCR6+ activated/memory ...
The ability of stem/progenitor cells to migrate and engraft into host tissues is key to their potent...
Hypoxia is a common feature of solid tumors that plays an important role in angiogenesis, malignant ...
Hypoxia is a condition of low oxygen tension occurring in inflammatory tissues. Dendritic cells (DC)...
Background: One of the most important stimuli in stem cell biology is oxygen. Chemokine receptor 4 (...
Hypoxia is a major characteristic of the solid tumor microenvironment. To understand how chimeric an...
Cancer cells, due to rapid cell proliferation, experience hypoxia as the tumor growth exceeds blood ...
Foxp3+ regulatory T cells migrate along blood vessels and at the tumor-stroma border. Regulatory T c...
The glycolytic response of hypoxic cells is primarily mediated by the hypoxia inducible factor alpha...
Cancer cells in hypoxic areas of solid tumors are to a large extent protected against the action of ...
Both malignant and stromal components in tumors are influenced by the physiologic conditions of the ...
The chemokine receptor CXCR4 plays a central role in organ-specific homing and tumor spreading and i...
Hypoxia within a tumor acts as a strong selective pressure that promotes angiogenesis, invasion, and...
The tumor microenvironment is characterized to be under severe conditions (nutrient shortage, low pH...
Migration of Foxp3+ regulatory T-lymphocytes is stopped in response to hypoxia. Regulatory T-lymphoc...
Migration of CXCR6+ activated/memory T-cells in the tumor microenvironment. CXCR6+ activated/memory ...
The ability of stem/progenitor cells to migrate and engraft into host tissues is key to their potent...
Hypoxia is a common feature of solid tumors that plays an important role in angiogenesis, malignant ...
Hypoxia is a condition of low oxygen tension occurring in inflammatory tissues. Dendritic cells (DC)...
Background: One of the most important stimuli in stem cell biology is oxygen. Chemokine receptor 4 (...
Hypoxia is a major characteristic of the solid tumor microenvironment. To understand how chimeric an...
Cancer cells, due to rapid cell proliferation, experience hypoxia as the tumor growth exceeds blood ...
Foxp3+ regulatory T cells migrate along blood vessels and at the tumor-stroma border. Regulatory T c...
The glycolytic response of hypoxic cells is primarily mediated by the hypoxia inducible factor alpha...
Cancer cells in hypoxic areas of solid tumors are to a large extent protected against the action of ...
Both malignant and stromal components in tumors are influenced by the physiologic conditions of the ...
The chemokine receptor CXCR4 plays a central role in organ-specific homing and tumor spreading and i...
Hypoxia within a tumor acts as a strong selective pressure that promotes angiogenesis, invasion, and...
The tumor microenvironment is characterized to be under severe conditions (nutrient shortage, low pH...