Protein tyrosine phosphatases - from housekeeping enzymes to master regulators of signal transduction

Now, as we try to define how phosphorylation-dependent cell signalling pathways are integrated at the level of the whole organism, it is important to understand fully the function of the protein phosphatases. This Special Issue of FEBS Journal presents articles that reflect the theme of specificity in protein phosphatase function and emphasize the critical role played by these enzymes in the regulation of signal transduction