We present genetic evidence that three presumptive protein kinases of Schizosaccharomyces pombe, byr2, byr1, and spk1 that are structurally related to protein kinases of Saccharomyces cerevisiae, STE11, STE7, and FUS3, respectively, are also functionally related. In some cases, introduction of the heterologous protein kinase into a mutant was sufficient for complementation. In other cases (as in a ste11- mutant of S. cerevisiae), expression of two S. pombe protein kinases (byr2 and byr1) was required to observe complementation, suggesting that byr2 and byr1 act cooperatively. Complementation in S. pombe mutants is observed as restoration of sporulation and conjugation and in S. cerevisiae as restoration of conjugation, pheromone-induced cel...
AbstractFilamentous invasive growth of S. cerevisiae requires multiple elements of the mitogen-activ...
Mitogen-activated protein kinase kinase kinase-Ste11 (MAPKKK-Ste11), MAPKK-Ste7, and MAPK-Kss1 media...
AbstractThe yeast mating factor-activated protein kinase pathway is a paradigm for understanding rel...
A conserved MAP kinase cascade is central to signal transduction in both simple and complex eukaryot...
We have shown that the expression of mam2, the gene encoding the Schizosaccharomyces pombe P-factor ...
Byr2 protein kinase, a homolog of mammalian mitogen-activated protein kinase/extracellular signal-re...
We describe a protein kinase, Shk1, from the fission yeast Schizosaccharomyces pombe, which is struc...
Protein kinases are well known to transmit and regulate signaling pathways. To identify additional r...
The STE11 gene of Saccharomyces cerevisiae is one of several genes required for mating between two h...
STE4 encodes the beta-subunit of a heterotrimeric guanine nucleotide-binding protein (G protein) tha...
Protein phosphorylation plays an important role in pheromone-induced differentiation processes of ha...
Ste7p and Mkk1p are MEK (MAPK/ERK kinase) family members that function in the mating and cell integr...
AbstractThe mechanisms whereby different external cues stimulate the same mitogen-activated protein ...
Mating pheromone stimulates a mitogen-activated protein (MAP) kinase activation pathway in Saccharom...
AbstractBackground: In the budding yeast Saccharomyces cerevisiae, components of a single mitogen-ac...
AbstractFilamentous invasive growth of S. cerevisiae requires multiple elements of the mitogen-activ...
Mitogen-activated protein kinase kinase kinase-Ste11 (MAPKKK-Ste11), MAPKK-Ste7, and MAPK-Kss1 media...
AbstractThe yeast mating factor-activated protein kinase pathway is a paradigm for understanding rel...
A conserved MAP kinase cascade is central to signal transduction in both simple and complex eukaryot...
We have shown that the expression of mam2, the gene encoding the Schizosaccharomyces pombe P-factor ...
Byr2 protein kinase, a homolog of mammalian mitogen-activated protein kinase/extracellular signal-re...
We describe a protein kinase, Shk1, from the fission yeast Schizosaccharomyces pombe, which is struc...
Protein kinases are well known to transmit and regulate signaling pathways. To identify additional r...
The STE11 gene of Saccharomyces cerevisiae is one of several genes required for mating between two h...
STE4 encodes the beta-subunit of a heterotrimeric guanine nucleotide-binding protein (G protein) tha...
Protein phosphorylation plays an important role in pheromone-induced differentiation processes of ha...
Ste7p and Mkk1p are MEK (MAPK/ERK kinase) family members that function in the mating and cell integr...
AbstractThe mechanisms whereby different external cues stimulate the same mitogen-activated protein ...
Mating pheromone stimulates a mitogen-activated protein (MAP) kinase activation pathway in Saccharom...
AbstractBackground: In the budding yeast Saccharomyces cerevisiae, components of a single mitogen-ac...
AbstractFilamentous invasive growth of S. cerevisiae requires multiple elements of the mitogen-activ...
Mitogen-activated protein kinase kinase kinase-Ste11 (MAPKKK-Ste11), MAPKK-Ste7, and MAPK-Kss1 media...
AbstractThe yeast mating factor-activated protein kinase pathway is a paradigm for understanding rel...