Integrins modulate signaling by growth factor receptors, but their role during tumorigenesis is not clear. Guo et al. (2006) now demonstrate that alpha 6 beta 4 integrin cooperates with ErbB2 in the formation of mammary tumors and discover distinct pathways that regulate cellular proliferation and adhesion downstream of the ErbB2-integrin complex
The work presented herein examines the potential impact of extracellular matrix (ECM) protein-integr...
beta 4 integrin and focal adhesion kinase (FAK) are often associated with a poor prognosis in cancer...
We previously demonstrated that beta(4) integrin subunit overexpression increases in vitro invasiven...
Integrins modulate signaling by growth factor receptors, but their role during tumorigenesis is not ...
SummaryAmplification of the ErbB2 locus, which encodes a receptor tyrosine kinase, is common in aggr...
SummaryAmplification of the ErbB2 locus, which encodes a receptor tyrosine kinase, is common in aggr...
ErbB2 is a member of the ErbB family of tyrosine kinase receptors that plays a major role in breast ...
Integrins modulate signaling by growth factor receptors, but their role during tumorigenesis is not ...
The integrin alpha(6)beta(4) has been shown to facilitate key functions of carcinoma cells, includin...
ErbB2 (HER2, Neu) and Ras play key roles in tumor invasion and metastasis. We identified a novel mec...
ERBB2 is a member of the ERBB family of tyrosine kinase receptors that plays a major role in breast ...
Interactions with the extracellular matrix (ECM) through integrin adhesion receptors provide cancer ...
ERBB2 is a member of the ERBB family of tyrosine kinase receptors that plays a major role in breast ...
Item does not contain fulltextInteractions with the extracellular matrix (ECM) through integrin adhe...
Blockade of the mitogen-activated protein (MAP) kinase pathway suppresses growth of colon cancer in ...
The work presented herein examines the potential impact of extracellular matrix (ECM) protein-integr...
beta 4 integrin and focal adhesion kinase (FAK) are often associated with a poor prognosis in cancer...
We previously demonstrated that beta(4) integrin subunit overexpression increases in vitro invasiven...
Integrins modulate signaling by growth factor receptors, but their role during tumorigenesis is not ...
SummaryAmplification of the ErbB2 locus, which encodes a receptor tyrosine kinase, is common in aggr...
SummaryAmplification of the ErbB2 locus, which encodes a receptor tyrosine kinase, is common in aggr...
ErbB2 is a member of the ErbB family of tyrosine kinase receptors that plays a major role in breast ...
Integrins modulate signaling by growth factor receptors, but their role during tumorigenesis is not ...
The integrin alpha(6)beta(4) has been shown to facilitate key functions of carcinoma cells, includin...
ErbB2 (HER2, Neu) and Ras play key roles in tumor invasion and metastasis. We identified a novel mec...
ERBB2 is a member of the ERBB family of tyrosine kinase receptors that plays a major role in breast ...
Interactions with the extracellular matrix (ECM) through integrin adhesion receptors provide cancer ...
ERBB2 is a member of the ERBB family of tyrosine kinase receptors that plays a major role in breast ...
Item does not contain fulltextInteractions with the extracellular matrix (ECM) through integrin adhe...
Blockade of the mitogen-activated protein (MAP) kinase pathway suppresses growth of colon cancer in ...
The work presented herein examines the potential impact of extracellular matrix (ECM) protein-integr...
beta 4 integrin and focal adhesion kinase (FAK) are often associated with a poor prognosis in cancer...
We previously demonstrated that beta(4) integrin subunit overexpression increases in vitro invasiven...
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