Laparoscopic management of bowel endometriosis: resection margins as a predictor of recurrence

Objective To evaluate possible predictive factors for recurrence after laparoscopic segmental bowel resection for bowel endometriosis. Design Cohort study. Setting Academic tertiary referral center.Methods 95 symptomatic women with bowel endometriosis who underwent laparoscopic segmental bowel resection at the Endometriosis clinic, University of Berne, between 2002 and 2012 were enrolled. Since 14 women were lost to follow-up, 81 formed the final cohort. Clinical and histological characteristics were examined as possible predictive factors for disease recurrence.Main outcome measures Recurrence, defined as a subsequent operation due to recurrent endometriosis-associated pain with a histologically confirmed endometriotic lesion.Results Recurrence was observed in 13 (16%) patients. Variables that were significantly associated to recurrence by the Cox regression analysis were positive bowel resection margins (hazard ratio 6.5, 95% confidence interval 1.8-23.5, p = 0.005), ag