Role of Exocrine and Endocrine Insufficiency in the Management of Patients with Chronic Pancreatitis
- Diéguez Castillo, Carmelo
- Jiménez Luna, Cristina
- Martín Ruiz, José Luis
- Martínez-Galán, Joaquina
- Prados Salazar, José Carlos
- Torres, Carolina
- González Ramírez, Amanda Rocío
- Caba Pérez, Octavio
DOIAbstract
Background: Exocrine pancreatic insufficiency results from the destruction of the pancreatic parenchyma and is diagnosed by using direct or indirect tests, both of which have shortcomings. Chronic pancreatitis is the most frequent cause of this pathology in adults. Methods: Patients meeting radiological or histological diagnostic criteria of chronic pancreatitis are enrolled and the stool elastase test is conducted, considering fecal elastase levels >200 µg/g to represent normal pancreatic function, and levels <200 µg/g to indicate the presence of exocrine pancreatic insufficiency. Additionally, we determine the body mass index of the patients and study their nutritional status and main biochemical and hematological variables, includ...
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