JNK-Dependent cJun Phosphorylation Mitigates TGFβ- and EGF-Induced Pre-Malignant Breast Cancer Cell Invasion by Suppressing AP-1-Mediated Transcriptional Responses
- Sundqvist, A. (Anders)
- Voytyuk, O. (Oleksandr)
- Hamdi, M. (Mohamed)
- Popeijus, H.E. (Herman)
- van der Burgt, C.B. (Corina Bijlsma-)
- Janssen, J. (Josephine)
- Martens, J.W.M. (John)
- Moustakas, A. (Aristidis)
- Heldin, C.-H. (C.)
- Dijke, P. (Peter) ten
- Dam, H. (Hans) van
DOIAbstract
Transforming growth factor-β (TGFβ) has both tumor-suppressive and tumor-promoting effects in breast cancer. These functions are partly mediated through Smads, intracellular transcriptional effectors of TGFβ. Smads fo
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