Percutaneous coronary intervention versus coronary artery bypass grafting in patients with three-vessel or left main coronary artery disease: 10-year follow-up of the multicentre randomised controlled SYNTAX trial
- Thuijs D. J. F. M.
- Kappetein A. P.
- Serruys P. W.
- Mohr F. -W.
- Morice M. -C.
- Mack M. J.
- Holmes D. R.
- Curzen N.
- Davierwala P.
- Noack T.
- Milojevic M.
- Dawkins K. D.
- da Costa B. R.
- Juni P.
- Head S. J.
- Casselman F.
- de Bruyne B.
- Hoj Christiansen E.
- Ruiz-Nodar J. M.
- Vermeersch P.
- Schultz W.
- Sabate M. (ORCID:0000-0001-6635-4985)
- Guagliumi G.
- Grubitzsch H.
- Stangl K.
- Darremont O.
- Bentala M.
- den Heijer P.
- Preda I.
- Stoler R.
- Szerafin T.
- Buckner J. K.
- Guber M. S.
- Verberkmoes N.
- Akca F.
- Feldman T.
- Beyersdorf F.
- Drieghe B.
- Oldroyd K.
- Berg G.
- Jeppsson A.
- Barber K.
- Wolschleger K.
- Heiser J.
- van der Harst P.
- Mariani M. A.
- Reichenspurner H.
- Stark C.
- Laine M.
- Ho P. C.
- Chen J. C.
- Zelman R.
- Horwitz P. A.
- Bochenek A.
- Krauze A.
- Grothusen C.
- Dudek D.
- Heyrich G.
- Kolh P.
- LeGrand V.
- Coelho P.
- Ensminger S.
- Nasseri B.
- Ingemansson R.
- Olivecrona G.
- Escaned J.
- Guera R.
- Berti S.
- Chieffo A.
- Burke N.
- Mooney M.
- Spolaor A.
- Hagl C.
- Nabauer M.
- Suttorp M. J.
- Stine R. A.
- McGarry T.
- Lucas S.
- Endresen K.
- Taussig A.
- Accola K.
- Canosi U.
- Horvath I.
- Cannon L.
- Talbott J. D.
- Akins C. W.
- Kramer R.
- Aschermann M.
- Killinger W.
- Narbute I.
- Burzotta F. (ORCID:0000-0002-6569-9401)
- Bogers A.
- Zijlstra F.
- Eltchaninoff H.
- Berland J.
- Stefanini G.
- Cruz Gonzalez I.
- Hoppe U.
- Kiesz S.
- Gora B.
- Ahlsson A.
- Corbascio M.
- Bilfinger T.
- Carrie D.
- Tchetche D.
- Hauptman K. -E.
- Stahle E.
- James S.
- Sandner S.
- Laufer G.
- Lang I.
- Witkowski A.
- Thourani V.
- Suryapranata H.
- Redwood S.
- Knight C.
- MacCarthy P.
- de Belder A.
- Banning A.
- Gershlick A.
DOIAbstract
Background: The Synergy between PCI with Taxus and Cardiac Surgery (SYNTAX) trial was a non-inferiority trial that compared percutaneous coronary intervention (PCI) using first-generation paclitaxel-eluting stents with coronary artery bypass grafting (CABG) in patients with de-novo three-vessel and left main coronary artery disease, and reported results up to 5 years. We now report 10-year all-cause death results. Methods: The SYNTAX Extended Survival (SYNTAXES) study is an investigator-driven extension of follow-up of a multicentre, randomised controlled trial done in 85 hospitals across 18 North American and European countries. Patients with de-novo three-vessel and left main coronary artery disease were randomly assigned (1:1) to the PCI...
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