Two oxazolidine-2-thiones, thio-analogs of linezolid, were synthesized and their antibacterial properties evaluated. Unlike oxazolidinones, the thio-analogs did not inhibit the growth of Gram positive bacteria. A molecular modeling study has been carried out to aid understanding of this unexpected finding
In recent years, the incidence of increase in bacterial resistance to a number of available antimicr...
Since the introduction in the pharmaceutical market of linezolid, an oxazolidin-2-one based new clas...
Novel oxazolidinone antibacterials bearing a variety of 3-indolylglyoxamide substituents have been e...
Two oxazolidine-2-thiones, thio-analogs of linezolid, were synthesized and their antibacterial prope...
In an effort to discover potent antibacterials based on the entropically favored "bioactive conforma...
The rising incidence of multidrug resistance in Gram-positive pathogen bacteria represents one of th...
Oxazolidinones are a class of antibacterial agents which displayed activity againist a variety of gr...
Oxazolidinones are prominent among the new Gram-positive antimicrobial agents now becoming available...
This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as a new class ...
This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as ...
This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as a new class ...
Abstract: Several oxazolidinones, which are a new class of synthetic antibacterial agents, display b...
The oxazolidinones are a new chemical class of synthetic antimicrobials characterized by a unique me...
The development of resistance by the antibiotics in the Gram-positive pathogenic bacteria over the l...
A series of conformationally constrained analogues of Linezolid were synthesised by employing a tand...
In recent years, the incidence of increase in bacterial resistance to a number of available antimicr...
Since the introduction in the pharmaceutical market of linezolid, an oxazolidin-2-one based new clas...
Novel oxazolidinone antibacterials bearing a variety of 3-indolylglyoxamide substituents have been e...
Two oxazolidine-2-thiones, thio-analogs of linezolid, were synthesized and their antibacterial prope...
In an effort to discover potent antibacterials based on the entropically favored "bioactive conforma...
The rising incidence of multidrug resistance in Gram-positive pathogen bacteria represents one of th...
Oxazolidinones are a class of antibacterial agents which displayed activity againist a variety of gr...
Oxazolidinones are prominent among the new Gram-positive antimicrobial agents now becoming available...
This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as a new class ...
This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as ...
This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as a new class ...
Abstract: Several oxazolidinones, which are a new class of synthetic antibacterial agents, display b...
The oxazolidinones are a new chemical class of synthetic antimicrobials characterized by a unique me...
The development of resistance by the antibiotics in the Gram-positive pathogenic bacteria over the l...
A series of conformationally constrained analogues of Linezolid were synthesised by employing a tand...
In recent years, the incidence of increase in bacterial resistance to a number of available antimicr...
Since the introduction in the pharmaceutical market of linezolid, an oxazolidin-2-one based new clas...
Novel oxazolidinone antibacterials bearing a variety of 3-indolylglyoxamide substituents have been e...
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