Biomimetic Understanding to Fabrication of Artificial Basilar Membrane, Blood-Brain Barrier Microchips with SAW devices

Presented on July 23, 2020 from 11:00 a.m.-12:00 p.m. SENIC Ambassadors Webinar Series: Biomimetic Understanding to Fabrication of Artificial Basilar Membrane, Blood-Brain Barrier Microchip, and SAW devicesThe Southeastern Nanotechnology Infrastructure Corridor (SENIC) housed at the Institute for Electronics and Nanotechnology at Georgia Tech hosted a series of online seminars. SENIC Ambassadors are faculty members from different academic institutions who support SENIC user programs and interests on their individual campuses.Southeastern Nanotechnology Infrastructure Corridor (SENIC) Ambassadors Webinar Series.Dr. Sourav Banerjee is an Associate Professor of Mechanical Engineering at University of South Carolina (UofSC). Before joining UofSC Dr. Banerjee served as Senior Research Scientist and then Director of Product Development in Acellent Technologies Inc. during 2008 and 2011. Dr. Banerjee’s research is focused on Ultrasonic and Acoustic waves while catering to multiple fields including ultrasonic wave based biomedical device applications. He serves in the editorial board of Scientific Reports published by Nature Publishing Group, International Aeronautics Journal, International Journal of Aeronautics and Aerospace Engineering. Dr. Banerjee also serve as an advisory board member of the Journal of Nondestructive Evaluation, Diagnostics and Prognostics of Engineering Systems, published by ASME. He has numerous research and teaching awards such as Achenbach Medal, 2010, Michael J. Mungo Award 2017, SHM person of the year award (2019) etc. for his contribution. Dr. Banerjee received Ph.D. in Engineering Mechanics and Applied Mathematics from University of Arizona, Tucson, USA in 2005.Runtime: 41:40 minutesMicroelectromechanical systems (MEMS) are gradually transforming at the interface of biology for multiple novel applications in the future. Integrated Material Assessment and Predictive Simulation Laboratory (i-MAPS) at the University of South Carolina (UofSC) has significant thrust on acoustical biomimetic for various applications. The approach is primarily based on observation, modeling and fabrication. All applications are derived from natural acoustic processes that we tend to ignore but naturally developed in the mammalian body. Through observation of the mechanism, understanding of the physics is derived from modified optimized physics-based models. Upon confirmation, the systems are fabricated for testing and validation. a) Inspired by the human cochlea, which is a magnificent acoustic device, an artificial basilar membrane is fabricated for potential use as mechanical Fourier Transformer. The device has potential applications in artificial hearing aids and artificial hearing devices for efficient human-robot interactions in the future. b) Natural transport of medicine and molecules through blood-brain-barrier (BBB) is challenging, however, with the aid of acoustical perturbation it is found to have increased absorption. Through understanding the physical mechanism acoustically aided artificial BBB are researched with neural experiments in acoustically aided microfluidic system. c) The lab-on-a-chip devices are very effective in sensing different mechanical and physical parameters related to biosensing, irrespective of their field of application, but has noticeable limitations. The limitation comes mostly from the demands posed by the users in a simultaneous sensing and the actuation environment, employing mutually exclusive physics and mechanisms. To overcome such limitations, acoustic waves devices are proposed for both sensing and actuation in a single platform simultaneously. The physics of surface acoustic wave (SAW) is one valuable physics used in MEMS that gives SAW devices to cover a wide range of applications such as filters, oscillators, transformers, sensors and actuators for biosensing