Rehabilitation in regenerative medicine: regenerative rehabilitation

Clinical application of regenerative medicine is steadily advancing nowadays, and some cell therapies have already reached patients in need. However, in many cases, there are issues due to which patients were not able to adequately restore their function by just cell transplantation.Recently, the importance of rehabilitation is being revealed in the field of regenerative medicine; therefore, a new research field, Regenerative Rehabilitation, has emerged. A factor in the success of cell therapy is optimization of microenvironments both at the site of cell transplantation and around it. Rehabilitative approaches will be able to optimize one of the microenvironments such as the environment of mechanical stress and temperature. To put this into practice, we need to verify the effects of physical therapy on transplanted and endogenous cells and its mechanisms, safety, economics, and possibility for clinical application. These are the fields that physical therapists can apply their specialty and experiences on adding or modifying mechanical stress. We hope that many physical therapists will join the field of Regenerative Rehabilitation