Sleep disorders in Latin-American children with asthma and/or allergic rhinitis and normal controls

Background: Asthma and/or allergic rhinitis have been associated with sleep disorders. The aim of this study was to evaluate sleep disorders in Latin-American children (4-10 years) from nine countries, with persistent asthma (A) and/or allergic rhinitis (AR) and in normal controls (C). Methods: Parents from 454 C children and 700 A and/or AR children followed up in allergy reference clinics completed the Children's Sleep Habits Questionnaire (CSHQ) which is aretrospective one-week questionnaire composed of 33 questions composed of seven subscales (bedtime resistance, sleep duration, sleep anxiety, night wakings, parasomnias, sleep disordered breathing and daytime sleepiness). The total scale of CSHQ and the subscales were compared between groups C and A+AR, A (n = 285) vs. AR (n = 390), and between controlled A (CA, n=103) vs. partially controlled/uncontrolled A (UA, n=182). Results: The comparison between C and A+AR showed no significant differences in age (6.7 years vs. 7.0 years, respectively), mean Body Mass Index and total scale of CSHQ (53.3 vs. 63.2, respectively) and the subscales were significantly higher in the A+AR group. Comparison between groups A and AR, except for sleep anxiety, showed significantly higher values for CSHQ total scale (66.9 vs. 61.0, respectively) and subscales for group A. The UA group showed significantly higher values for total CSHQ scale and subscales in comparison to CA (71.1 vs. 59.4, respectively). Conclusions: Latin-American children with asthma and/or allergic rhinitis showed sleep disorders identified by the CSHQ when compared to normal controls. Despite being treated, asthma causes sleep impairment, especially when uncontrolled. (C) 2016 SEICAP. Published by Elsevier Espana, S.L.U. All rights reserved.Unipampa Fed Univ, Uruguaiana, Rio Grande Sul, BrazilUniv Fed Sao Paulo, Div Allergy & Clin Immunol, Sao Paulo, BrazilUniv Fed Parana, Dept Pediat, Curitiba, Parana, BrazilDr Avelino L Castelan Pediat Hosp, Chaco, ArgentinaHosp Univ Metropolitano, Barranquilla, ColombiaHosp Univ Gen Calixto Garcia, Havana, CubaCtr Asma & Alergia, Tegucigalpa, HondurasCtr Med San Angel, Xalapa, Veracruz, MexicoClin Alergia & Asma, Asuncion, ParaguayCtr Med Avanzada Dr Abel Gonzalez, Santo Domingo, Dominican RepHosp Pediat Pereira Rossell, Montevideo, UruguayClin Reg Este, Cordoba, ArgentinaCtr Nacl Biopreparados, Havana, CubaCtr Pesquisa Consultorios Med Familia, Havana, CubaHosp Univ Infantil, Santiago De Cuba, CubaHosp ISSSTE, Allergy Serv, Mexico City, Veracruz, MexicoUniv Nacl Este, Asuncion, ParaguayABC Fdn, Sch Med, Santo Andre, BrazilUniv Fed Sao Paulo, Div Allergy & Clin Immunol, Sao Paulo, BrazilWeb of Scienc