Fast dissolving tablets: a novel approach

An oral route of drug administration is the most popular route of administration. It have wide acceptance up to 50-60% of total dosage forms. Tablet is the most popular dosage forms existing today because of its convenience of self administration, compactness and easy manufacturing; however hand tremors, dysphasia in case of geriatric patients, the underdeveloped muscular and nervous systems in young individuals and case of uncooperative patients, the problem of swallowing is common phenomenon which leads to poor patient compliance. Mouth dissolving tablets (FDT) or fast dissolving tablets; (FDT) has emerged as alternative oral dosage forms. These are novel types of tablets that disintegrate/dissolve/disperse in saliva within few seconds. Fast dissolving tablets (FDTs) have received ever-increasing demand during the last decade, and the field has become a rapidly growing area in the pharmaceutical industry. This article reviews the Need, advantages, challenges, limitations, mechanism of superdisintegrants, various formulation technologies (conventional and patented), marketed product of Fast dissolving tablets