Antioxidant and Antimicrobial Activities of Methanolic Leaves Extract of Lagerstroemia parviflora

An antioxidant is a molecule capable of terminating the chain reactions that damage cells by removing free radical intermediates and inhibit other oxidation reactions by thereby reducing stress responsible for many degenerative disorders. The present study was concerned with phytochemical screening, antioxidant, antimicrobial activities of methanolic leaves extract of Lagerstroemia parviflora. It was observed that the methanol extract showed IC 50 value of 76.05µg/ml as compare to standard ascorbic acid 14.66 µg/ml. It was evident that the extracts showed proton-donating ability and this could serve as free radical inhibitors or scavengers, acting possibly as primary antioxidants. Thus the methanol extract of this plant possesses the strongest ability to scavenge DPPH radical. The leaves extracts of Lagerstroemia parviflora exhibited potential antibacterial activity against Staphylococcus aureus (20±0.2, 21±0.1 and 23±0.1), Salmonella bongori (9±0.3, 12±0.1and 15±0.5) and Aspergillus niger (7±0.1, 9±0.1 and 11±0.2) at the concentration level of 25-100mg/ml. The Results of antimicrobial activity of extract showd more effectiveness against both the selected bacteria (Staphylococcus aureus and Salmonella bongori) found less effective against fungus (Aspergillus niger). The present study suggests that the use of leaves of this plant may be exploited for health supplements and has potential for topical treatment. Keywords: Lagerstroemia parviflora, Antioxidant, Antimicrobia