Herein we present a female patient aged 61 with Philadelphia negative acute lymphoblastic leukaemia demonstrating near haploid karyotype and abnormal TP53 expression at diagnosis, who relapsed with lineage switch as Acute Monocytic Leukemia post allogeneic stem cell transplantation. Molecular analysis established that both neoplasms were derived from the same founder clone. The leukemic lineage switch phenomenon has recently re-attracted interest as mechanism of leukemic evasion post treatment with chimeric antigen receptor T-cells but there is paucity of data on its presence post allograft or following novel antibody treatments such as Inotuzumab Ozogamicin or Blinatumomab. Our proposition for cancer research is that near haploidy in ALL c...
International audienceBackground: A large number of chromosomal translocations of the human KMT2A ge...
A unique case of primary refractory FLT3-itd mutated acute myeloid leukemia in an elderly patient, w...
Background: Myelodysplastic syndromes and acute leukemias after allogeneic stem cell transplantation...
Herein we present a female patient aged 61 with Philadelphia negative acute lymphoblastic leukaemia ...
Herein we present a female patient aged 61 with Philadelphia negative acute lymphoblastic leukaemia ...
An 18-month-old girl was diagnosed with prepre-B ALL/t(4;11) leukemia, which during thetreatment and...
An 18-month-old girl was diagnosed with prepre-B ALL/t(4;11) leukemia, which during thetreatment and...
Concurrent hematologic malignancies are relatively rare. We encountered a case of concurrent acute m...
OnlinePublDonor-derived haematological neoplasms, in which recipients present with haematological ma...
Acknowledgements: This research is funded by the Wellcome Trust (grants 206194 and 223135/Z/21/Z). T...
Donor-derived leukaemia is exceptional after allogeneic bone marrow transplantation (BMT). A woman w...
The patient reported here underwent hematopoietic stem cell transplantation (HSCT) due to chronic gr...
The patient reported here underwent hematopoietic stem cell transplantation (HSCT) due to chronic gr...
A 12-year-old girl presented with a CD33(+) precursor B-acute lymphoblastic leukaemia (ALL) and seem...
A 12-year-old girl presented with a CD33(+) precursor B-acute lymphoblastic leukaemia (ALL) and seem...
International audienceBackground: A large number of chromosomal translocations of the human KMT2A ge...
A unique case of primary refractory FLT3-itd mutated acute myeloid leukemia in an elderly patient, w...
Background: Myelodysplastic syndromes and acute leukemias after allogeneic stem cell transplantation...
Herein we present a female patient aged 61 with Philadelphia negative acute lymphoblastic leukaemia ...
Herein we present a female patient aged 61 with Philadelphia negative acute lymphoblastic leukaemia ...
An 18-month-old girl was diagnosed with prepre-B ALL/t(4;11) leukemia, which during thetreatment and...
An 18-month-old girl was diagnosed with prepre-B ALL/t(4;11) leukemia, which during thetreatment and...
Concurrent hematologic malignancies are relatively rare. We encountered a case of concurrent acute m...
OnlinePublDonor-derived haematological neoplasms, in which recipients present with haematological ma...
Acknowledgements: This research is funded by the Wellcome Trust (grants 206194 and 223135/Z/21/Z). T...
Donor-derived leukaemia is exceptional after allogeneic bone marrow transplantation (BMT). A woman w...
The patient reported here underwent hematopoietic stem cell transplantation (HSCT) due to chronic gr...
The patient reported here underwent hematopoietic stem cell transplantation (HSCT) due to chronic gr...
A 12-year-old girl presented with a CD33(+) precursor B-acute lymphoblastic leukaemia (ALL) and seem...
A 12-year-old girl presented with a CD33(+) precursor B-acute lymphoblastic leukaemia (ALL) and seem...
International audienceBackground: A large number of chromosomal translocations of the human KMT2A ge...
A unique case of primary refractory FLT3-itd mutated acute myeloid leukemia in an elderly patient, w...
Background: Myelodysplastic syndromes and acute leukemias after allogeneic stem cell transplantation...