Impact of Circadian Blood Pressure Pattern on Silent Cerebral Small Vessel Disease: A Systematic Review and Meta-Analysis.
- Chokesuwattanaskul, Anthipa
- Cheungpasitporn, Wisit
- Thongprayoon, Charat
- Vallabhajosyula, Saraschandra
- Bathini, Tarun
- Mao, Michael A
- Cato, Liam D
- Chokesuwattanaskul, Ronpichai
DOIAbstract
Background Abnormal circadian blood pressure (BP) variations during sleep, specifically the non-dipping (<10% fall in nocturnal BP) and reverse-dipping patterns (rise in nocturnal BP), have been associated with an increased risk of cardiovascular events and target organ damage. However, the relationship between abnormal sleep BP variations and cerebral small vessel disease markers is poorly established. This study aims to assess the association between non-dipping and reverse-dipping BP patterns with markers of silent cerebral small vessel disease. Methods and Results MEDLINE, Embase, and Cochrane Databases were searched from inception through November 2019. Studies that reported the odds ratios (ORs) for cerebral small vessel disease marke...
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