Chemical investigation of Methanolic Extract of Piper betle Linn (Leaf stalk)

oai:ojs2.sriopenjournals.com:article/21Natural products have been a major source of drugs for centuries. The leaf stalk of Piper betle is used traditionally known to be useful for the treatment of various diseases like bad breath, boils and abscesses, conjunctivitis, constipation, headache, itches, mastitis, mastoiditis, leucorrhoea, otorrhoea, swelling of gum, rheumatism, cuts, and injuries. The main objective of this study is to carry out a phytochemical analysis of the methanol crude extract of the leaf stalk of P. betle. Phytochemical screening on this crude extract revealed the presence of phenols, alkaloids, steroids, terpenes, saponins, and flavonoids. After silica gel column chromatography, the crude extract led to the isolation of compound- 2-[4′-(3″-methylbut-2-en-oxy)-(3′,5′-dimethoxy)phenyl]-5-hydroxy-7-methoxy-Chromone-4 (PBT-V). Characterization of this compound was achieved via spectroscopic methods (NMR, UV, mass spectroscopy, and IR)