Preparation and fungitoxicity of some dichloro-8-quinolinols / Herman Gershon, Donald D. Clarke, and Muriel Gershon Department of Chemistry, Fordham University, Bronx, NY 10458, USA New York Botanical Garden, Bronx, NY 10458, USA

2,5-, 3,5-, 3,7-, 4,5-, 5,6-, und 6,7-Dichloro-8-quinolinols were prepared and tested along with their 3,6- and 5,7-ana1ogues against six fungi (Aspergillus niger, A. oryzae, Myrothecium verrucaria, Trichoderma viride, Mucor cirinelloides, and Trichophyton mentagrophytes) in Sabouraud dextrose broth. Most of the compounds were strongly antifungal, inhibiting five of the fungi below 1 μg/ml. This activity is attributed to intramolecular synergism. M. cirinelloides was inhibited less by these compound