The aim of the study is to investigate the patterns of polypharmacy, clinical-relevant drug-drug interactions (DDIs), and potentially inappropriate medicines (PIMs), and whether polypharmacy, potential serious clinically-relevant DDIs, or PIMs can be associated with low quality of life (QoL) index scores of older adults with type 2 diabetes (T2D). A cross-sectional study was conducted using data of 670 elderly T2D sub-cohort from a nationwide pharmacy-based intensive monitoring study of inception cohort of T2D in Portugal. 72.09% were found on polypharmacy (≥5 medicines). Participants on polypharmacy were mostly females (P = .0115); more obese (P = .0131); have more comorbid conditions (P < .0001); more diabetes complications (P < .0001); a...
Dichloroacetate (DCA) is an investigational drug targeting the glycolytic hallmark of cancer by inhi...
Background: Non‐adherence is a significant problem in bipolar disorder. Second‐generation antipsycho...
Introduction We evaluated the arginine-depleting enzyme pegargiminase (ADI-PEG20; ADI) with pemetre...
The aim of the study is to investigate the patterns of polypharmacy, clinical-relevant drug-drug int...
Background: Non-adherence is a significant problem in bipolar disorder. Second-generation antipsycho...
__Objective:__ Previous studies suggest that androgens have a sexually dimorphic impact on metabolic...
There is growing interest in utilizing pharmacogenetic (PGx) testing to guide antidepressant use, bu...
Purpose: Diabetic cardiomyopathy (DCM) can be cause of a progressive dysfunction of ventricular cont...
Introduction: Patients with NAFLD have a two‐fold increased risk of diabetes, and conversely, NAFLD ...
Decreased left ventricular (LV) diastolic function is associated with increased all-cause mortality ...
Background: In sub-Saharan Africa, adult outpatients with symptoms of acute infectious illness are ...
The phospholipid l-?-lysophosphatidylinositol (LPI), an endogenous ligand for GPR55, is elevated in ...
AimsTo investigate the relationship between fibro-inflammatory biomarkers and cardiovascular structu...
Objective: In focal epilepsy, data on the etiology-specific response to antiseizure medication (ASM)...
Aims beta-cell stress and dysfunction may contribute to islet autoimmunity and progression to clinic...
Dichloroacetate (DCA) is an investigational drug targeting the glycolytic hallmark of cancer by inhi...
Background: Non‐adherence is a significant problem in bipolar disorder. Second‐generation antipsycho...
Introduction We evaluated the arginine-depleting enzyme pegargiminase (ADI-PEG20; ADI) with pemetre...
The aim of the study is to investigate the patterns of polypharmacy, clinical-relevant drug-drug int...
Background: Non-adherence is a significant problem in bipolar disorder. Second-generation antipsycho...
__Objective:__ Previous studies suggest that androgens have a sexually dimorphic impact on metabolic...
There is growing interest in utilizing pharmacogenetic (PGx) testing to guide antidepressant use, bu...
Purpose: Diabetic cardiomyopathy (DCM) can be cause of a progressive dysfunction of ventricular cont...
Introduction: Patients with NAFLD have a two‐fold increased risk of diabetes, and conversely, NAFLD ...
Decreased left ventricular (LV) diastolic function is associated with increased all-cause mortality ...
Background: In sub-Saharan Africa, adult outpatients with symptoms of acute infectious illness are ...
The phospholipid l-?-lysophosphatidylinositol (LPI), an endogenous ligand for GPR55, is elevated in ...
AimsTo investigate the relationship between fibro-inflammatory biomarkers and cardiovascular structu...
Objective: In focal epilepsy, data on the etiology-specific response to antiseizure medication (ASM)...
Aims beta-cell stress and dysfunction may contribute to islet autoimmunity and progression to clinic...
Dichloroacetate (DCA) is an investigational drug targeting the glycolytic hallmark of cancer by inhi...
Background: Non‐adherence is a significant problem in bipolar disorder. Second‐generation antipsycho...
Introduction We evaluated the arginine-depleting enzyme pegargiminase (ADI-PEG20; ADI) with pemetre...