Add to ORKGThe formation of self-organized patterns is key to the morphogenesis of multicellular organisms, although a comprehensive theory of biological pattern formation is still lacking. Here, we propose a biologically realistic and unifying approach to emergent pattern formation. Our biphasic model of multicellular tissues incorporates turnover and transport of morphogens controlling cell differentiation and tissue mechanics in a single framework, where one tissue phase consists of a poroelastic network made of cells and the other is the extracellular fluid permeating between cells. While this model encompasses previous theories approximating tissues to inert monophasic media, such as Turing’s reaction-diffusion model, it overcomes some of their k...
How a system of genetically identical biological cells organizes into spatially heterogeneous tissue...
Embryonic development is a largely self-organizing process, in which the adult body plan arises from...
We present a mechanical model for cell aggregation in embryonic development. The model is based on t...
The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, alt...
The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, alt...
The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, alt...
The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, alt...
The reaction-diffusion models have been extensively applied to explain the mechanism of pattern form...
Motivated by recent experimental findings, we propose a novel mechanism of embryonic pattern formati...
Motivated by recent experimental findings, we propose a novel mechanism of embryonic pattern formati...
<div><p>Motivated by recent experimental findings, we propose a novel mechanism of embryonic pattern...
Background During embryogenesis, chemical (morphogen) and mechanical patterns develop within tiss...
International audiencePatterns are ubiquitous in living systems and underlie the dynamic organizatio...
<div><p>Chemical and mechanical pattern formation is fundamental during embryogenesis and tissue dev...
Chemical and mechanical pattern formation is fundamental during embryogenesis and tissue development...
How a system of genetically identical biological cells organizes into spatially heterogeneous tissue...
Embryonic development is a largely self-organizing process, in which the adult body plan arises from...
We present a mechanical model for cell aggregation in embryonic development. The model is based on t...
The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, alt...
The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, alt...
The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, alt...
The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, alt...
The reaction-diffusion models have been extensively applied to explain the mechanism of pattern form...
Motivated by recent experimental findings, we propose a novel mechanism of embryonic pattern formati...
Motivated by recent experimental findings, we propose a novel mechanism of embryonic pattern formati...
<div><p>Motivated by recent experimental findings, we propose a novel mechanism of embryonic pattern...
Background During embryogenesis, chemical (morphogen) and mechanical patterns develop within tiss...
International audiencePatterns are ubiquitous in living systems and underlie the dynamic organizatio...
<div><p>Chemical and mechanical pattern formation is fundamental during embryogenesis and tissue dev...
Chemical and mechanical pattern formation is fundamental during embryogenesis and tissue development...
How a system of genetically identical biological cells organizes into spatially heterogeneous tissue...
Embryonic development is a largely self-organizing process, in which the adult body plan arises from...
We present a mechanical model for cell aggregation in embryonic development. The model is based on t...