The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, although a comprehensive theory of biological pattern formation is still lacking. Here, we propose a minimal model combining tissue mechanics to morphogen turnover and transport in order to explore new routes to patterning. Our active description couples morphogen reaction-diffusion, which impact on cell differentiation and tissue mechanics, to a two-phase poroelastic rheology, where one tissue phase consists of a poroelastic cell network and the other of a permeating extracellular fluid, which provides a feedback by actively transporting morphogens. While this model encompasses previous theories approximating tissues to inert monophasic media, ...
Active self organization of structure is ubiquitous in nature. In a seminal work, Turing proposed a ...
Background: During embryogenesis, chemical (morphogen) and mechanical patterns develop within tissue...
We analyze a recently proposed model \cite{ABBM1}, for the regulation of growth and patterning in de...
The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, alt...
The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, alt...
The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, alt...
The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, alt...
The reaction-diffusion models have been extensively applied to explain the mechanism of pattern form...
<div><p>Motivated by recent experimental findings, we propose a novel mechanism of embryonic pattern...
Motivated by recent experimental findings, we propose a novel mechanism of embryonic pattern formati...
Background During embryogenesis, chemical (morphogen) and mechanical patterns develop within tiss...
Motivated by recent experimental findings, we propose a novel mechanism of embryonic pattern formati...
In this paper we propose a new mathematical model for describing the complex interplay between skin ...
<div><p>Chemical and mechanical pattern formation is fundamental during embryogenesis and tissue dev...
Chemical and mechanical pattern formation is fundamental during embryogenesis and tissue development...
Active self organization of structure is ubiquitous in nature. In a seminal work, Turing proposed a ...
Background: During embryogenesis, chemical (morphogen) and mechanical patterns develop within tissue...
We analyze a recently proposed model \cite{ABBM1}, for the regulation of growth and patterning in de...
The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, alt...
The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, alt...
The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, alt...
The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, alt...
The reaction-diffusion models have been extensively applied to explain the mechanism of pattern form...
<div><p>Motivated by recent experimental findings, we propose a novel mechanism of embryonic pattern...
Motivated by recent experimental findings, we propose a novel mechanism of embryonic pattern formati...
Background During embryogenesis, chemical (morphogen) and mechanical patterns develop within tiss...
Motivated by recent experimental findings, we propose a novel mechanism of embryonic pattern formati...
In this paper we propose a new mathematical model for describing the complex interplay between skin ...
<div><p>Chemical and mechanical pattern formation is fundamental during embryogenesis and tissue dev...
Chemical and mechanical pattern formation is fundamental during embryogenesis and tissue development...
Active self organization of structure is ubiquitous in nature. In a seminal work, Turing proposed a ...
Background: During embryogenesis, chemical (morphogen) and mechanical patterns develop within tissue...
We analyze a recently proposed model \cite{ABBM1}, for the regulation of growth and patterning in de...
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