Multifunctional hybrids based on 2D fluorinated graphene oxide and superparamagnetic iron oxide nanoparticles

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPCarbon-based nanomaterials have garnered a lot of attention in the research of yesteryear. Here this study reports a composite based on fluorinated graphene oxide-a multifunctional subsidiary of graphene; and iron oxide nano-particles as a contrast agent for magnetic resonance imaging (MRI). Extensive structural and functional characterization is carried out to understand composite behavior toward biotoxicity and its performance as a contrast agent. The electron withdrawing fluorine group decreases the charge transfer to iron oxide increasing the magnetic saturation of the composite thus enhancing the contrast. The interaction of paramagnetic and superparamagnetic systems yields a superior contrast agent for MRI and fluorescent imaging.341118FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP2013/08293-72016/12340-9S.R., C.S.T., and P.M.A. acknowledge the support from Air Force Office of Scientific Research (AFOSR) Grant No. FA9550-12-1-0035. C.F.W. and D.S.G. thank the Center for Computational Engineering and Sciences at Unicamp for financial support through the FAPESP/CEPID Grant #2013/08293-7. C.F.W. thanks Sao Paulo Research Foundation (FAPESP) Grant #2016/12340-9 for financial support