Anti-Nociceptive Formulation that works via Simultaneous Upregulation of PGE1 and Suppression of FMO3 Levels.

The invention relates to a composition formed for anti-inflammatory and analgesic treatment and to the use of said composition. State of the Art Analgesics are the most widely used medicaments of the present day. That they have only a low extent of side effects is the most significant reason why the analgesics are the primary medicaments that are most extensively used. Analgesics are available in almost every house. Analgesics are not always used in line with the actual requirement of the patient and the people unnecessarily request that the physicians include such drugs in the prescriptions. When not prescribed by a physician, they are purchased over-the-counter from the pharmacy just for the sake of keeping them available in the house. The analgesics are used without the recommendation of a physician for the cases of headache and joint pain. One of the most frequently made mistakes is the use of an analgesic prescribed by the physician for the treatment of another pain without consulting the physician. When one experiences headache, it may not be appropriate to use an analgesic prescribed by the physician for the joint pains. The reason is that the different active agents within the analgesics lead to different outcomes. The unnecessary or inappropriate analgesic use may lead to side effects in the liver and kidney patients. Analgesics increase the blood pressure and the heart rate. As a result, the unnecessary or inappropriate use of analgesics is very harmful for the patients with cardiac, vascular and cardiac rhythm problems. Also today, analgesic, or simply painkiller, is the name given to any kind of medication used to relieve the pain and cause analgesia. It is derived from the Greek words an- (without) and -algia (pain). Analgesic drugs act upon the peripheral and central nervous system. One of the oldest and most studied problems in history is to relieve the pain by the use of medicaments. The medicaments that act upon the central nervous system and are used to relieve the pain are generally referred to as analgesics. Since the oldest civilizations, the human being has used the agents obtained from the plants in order to relieve the pain. Opium is among the most widely used natural painkillers. Opium is a latex that exudates as a result of knife-scratching of the immature seed pods of opium poppy (papaver somniferum) and dries and solidifies on the pod under the influence of the sun. Around 23 types of alkaloids are present in the raw opium. Alkaloids generally have a heterocyclic structure and exhibit physiological action. The anesthetic action of the opium stems from the alkaloids it contains. These are generally called the opium alkaloids. Alkaloids are named based on the plant from which they are obtained (opium alkaloids, chinchona alkaloids, etc.) or their chemical structure (phenanthrene class of alkaloids, etc.). Opium alkaloids are divided into two according to their chemical structure: 1. Phenanthrene class: Morphine, Codeine, Thebaine, Fentanyl 2. Isoquinoline class: Papaverine, Narceine, Narcotine, Cotarnine Analgesics have many different kinds including paracetamol, anesthetic drugs (such as morphine), synthetic drugs with anesthetic effect (such as tramadol), NSAIDs (non-steroidal anti-inflammatory drugs). Some drug groups employed for the treatment of the neuropathic pain syndromes are not included in the analgesics. Anticonvulsants and tricyclic antidepressants may be given as examples of such drugs. According to the state of the art, the medicaments employed in order to suppress the chronic and acute inflammations and pains resulting from various diseases and traumas serve their function by way of suppressing the expression of cox-2 and pge-2. Since the drugs using this mode of action, which is principally an effective method, do not simultaneously stimulate the production of cox-1 and pge-1, the selective cox-2 and pge-2 suppressor components have side effects such as possible insulin resistance, stomach tissue damage, internal bleeding