COMPARISON OF QUALITY CONTROL OF PLATELET CONCENTRATES PRODUCED BY BUFFY COAT AND PLATELETPHERESIS METHOD

Cilj: Cilj ovog rada je utvrditi postoji li statistička razlika u volumenu i broju trombocita 1 doze koncentrata trombocita proizvedenih BC metodom i metodom trombafereze. Metode: Podaci o parametrima kontrole kvalitete koncentrata trombocita proizvedenih na oba načina za vremensko razdoblje od 1 godine (2017.g.) prikupljeni su u ZTM, KBC Split. Uspoređeni su prosječni mjesečni rezultati za volumen i broj trombocita po 1 dozi koncentrata trombocita korištenjem t-testa za 2 nezavisna uzorka. Rezultati: Dokazano je postojanje statistički značajne razlike u volumenu 1 doze koncentrata trombocita i broja trombocita u 1 dozi koncentrata trombocita uspoređivanjem 2 metoda proizvodnje koncentrata trombocita. Prosječni volumen 1 doze koncentrata trombocita proizvedenog BC metodom je 53,37 ml naspram 56,37 ml 1 doze koncentrata trombocita proizvedenog metodom trombafereze (p=0,0086). Broj trombocita u 1 dozi koncentrata trombocita proizvedenog BC metodom je 6,54 x1010/L naspram 5,02 x10 10/L po 1 dozi koncentrata trombocita proizvedenog metodom trombafereze (p<0,0001). Zaključci: Ovim istraživanjem dokazane su razlike u volumenu i broju trombocita po 1 dozi koncentrata trombocita proizvedenog BC metodom i metodom trombafereze u ZTM, KBC Split.Objective: The aim oft his study was to determine statistically significant difference in volume and platelet count per 1 dose of platelet concentrates produced by buffy-coat method and plateletpheresis. Methods: All data about quality control of platelet concentrates from 2017. produced by buffy coat method and plateletpheresis method were taken from ZTM, KBC Split. There were compared monthly average of volume per 1 dose of platelet concentrate and number of platelets per 1 dose of platelet concentrate. Statistic method t-test for two independent samples was used. Results: The results showed statistic significant difference in volume per 1 dose of platelet concentrate and number of platelets per 1 dose of platelet concentrate. The average volume per 1 dose of buffy coat produced platelet concentrate was 53,37 ml, while 56,37 ml was per 1 dose of plateletpheresis produced platelet concentrate (p=0.0086). The number of platelets per 1 dose of platelet concentrate produced by buffy coat was 6,54 x1010/L, while 5,02 x1010/L was per 1 dose of plateletpheresis produced platelet concentrate (p