Atrial myxomas arise from multipotent cardiac stem cells
- Scalise, Mariangela
- Torella, Michele
- Marino, Fabiola
- Ravo, Maria
- Giurato, Giorgio
- Vicinanza, Carla
- Cianflone, Eleonora
- Mancuso, Teresa
- Aquila, Iolanda
- Salerno, Luca
- Nassa, Giovanni
- Agosti, Valter
- De Angelis, Antonella
- Urbanek, Konrad
- Berrino, Liberato
- Veltri, Pierangelo
- Paolino, Donatella
- Mastroroberto, Pasquale
- De Feo, Marisa
- Viglietto, Giuseppe
- Weisz, Alessandro
- Nadal-Ginard, Bernardo
- Ellison-Hughes, Georgina M
- Torella, Daniele
DOIAbstract
Cardiac myxomas usually develop in the atria and consist of an acid-mucopolysaccharide-rich myxoid matrix with polygonal stromal cells scattered throughout. These human benign tumours are a valuable research model because of the rarity of cardiac tumours, their clinical presentation and uncertain origin. Here, we assessed whether multipotent cardiac stem/progenitor cells (CSCs) give rise to atrial myxoma tissue
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