A biological multiplexer, designs, and simulations

Biological circuits can be used in synthetic biology to perform logical functions similar to those observed in electronic circuits. These circuits are applied as a method to define cellular functions in useful ways. The purpose of this field of research is to design and simulate systems which can combine VLSI technology and biological circuits. In this regard, five different architectures (AND–OR, AND–NOR–OR–AND Full-NAND, and Full-NOR) of a new biomultiplexer have been designed and simulated. The results of these architectures are compared in terms of delay as well as the number of promoters and genes. The two-level architectures AND–OR, AND–NOR, and OR–AND, in addition to the greater number of genes and promoters, have also a longer execution time than the designs with two universal NAND or NOR gates. In Full-NAND design, the execution time is reduced by lowering the number of genes and the number of promoters. Finally, Full-NOR design offers the shortest execution time of 0.612 s, while reducing promoters by 64% and the number of genes by 50%, compared to other proposed architectures