Low rank problems are nonlinear minimization problems in which the objective function, by means of a suitable linear transformation of the variables, depends on very few variables. These problems often arise in quantitative management science applications, for example, in location models, transportation problems, production planning, data envelopment analysis, and multiobjective programs. They are usually approached by means of outer approximation, branch and bound, branch and select, and optimal level solution methods. The paper studies, from both a theoretical and an algorithmic point of view, a class of large dimension rank-two nonconvex problems having a polyhedral feasible region and $f(x)=phi(c^Tx+c_0,d^Tx+d_0)$ as the objective funct...