Add to ORKGThe Antipoxviral activities and phosphorylation of N-methanocarbathymidine ([N]-MCT) and four 5-halo-2\u27-deoxyuridines, namely 5-flouro- (FdU), 5-chloro- (CldU), 5-bromo- (BrdU), and 5-iodo- (IdU) derivatives were explored
The flavin-dependent thymidylate synthase X (ThyX), rare in eukaryotes and completely absent in huma...
Among the many prodrug approaches aimed at delivering nucleoside monophosphates into cells, the phos...
A series of novel dihydro-alkyloxy-benzyl-oxopyrimidine derivatives were synthesized and evaluated f...
The Antipoxviral activities and phosphorylation of N-methanocarbathymidine ([N]-MCT) and four 5-halo...
The search for effective therapies for orthopoxvirus infections has identified diverse classes of mo...
Anti-poxvirus therapies are currently limited to cidofovir [(S)-1-(3-hydroxy-2-phosphonylmethoxyprop...
International audienceAnti-poxvirus therapies are currently limited to cidofovir [(S)-1-(3-hydroxy-2...
5-Fluorouracil, 5-fluorouridine (FUrd), 5-fluoro-2'-deoxyuridine (FdUrd), 5-fluorocytidine (FCyd), 5...
Uridine-based nucleoside analogues have often been found to have relatively poor antiviral activity....
A novel carbocyclic thymidine analog, N-methanocarbathymidine [(N)-MCT], was evaluated for inhibitio...
5-Methoxymethyl-1-(2'-deoxy-beta-D-lyxofuranosyl)uracil (MMdLU) was not active against the herpes si...
We report the synthesis of a series of novel 2'-deoxy-2',2'-difluoro-5-halouridines and their corres...
2'-Fluoro-2'-deoxyguanosine has been reported to have potent anti-influenza virus activity in vitro ...
2′-Fluoro-2′-deoxyguanosine has been reported to have potent anti-influenza virus activity in vitro ...
The carbocyclic analogues of (E)-5-(2-bromovinyl)-2'-deoxyuridine (C-BVDU) and (E)-5-(2-iodovinyl)-2...
The flavin-dependent thymidylate synthase X (ThyX), rare in eukaryotes and completely absent in huma...
Among the many prodrug approaches aimed at delivering nucleoside monophosphates into cells, the phos...
A series of novel dihydro-alkyloxy-benzyl-oxopyrimidine derivatives were synthesized and evaluated f...
The Antipoxviral activities and phosphorylation of N-methanocarbathymidine ([N]-MCT) and four 5-halo...
The search for effective therapies for orthopoxvirus infections has identified diverse classes of mo...
Anti-poxvirus therapies are currently limited to cidofovir [(S)-1-(3-hydroxy-2-phosphonylmethoxyprop...
International audienceAnti-poxvirus therapies are currently limited to cidofovir [(S)-1-(3-hydroxy-2...
5-Fluorouracil, 5-fluorouridine (FUrd), 5-fluoro-2'-deoxyuridine (FdUrd), 5-fluorocytidine (FCyd), 5...
Uridine-based nucleoside analogues have often been found to have relatively poor antiviral activity....
A novel carbocyclic thymidine analog, N-methanocarbathymidine [(N)-MCT], was evaluated for inhibitio...
5-Methoxymethyl-1-(2'-deoxy-beta-D-lyxofuranosyl)uracil (MMdLU) was not active against the herpes si...
We report the synthesis of a series of novel 2'-deoxy-2',2'-difluoro-5-halouridines and their corres...
2'-Fluoro-2'-deoxyguanosine has been reported to have potent anti-influenza virus activity in vitro ...
2′-Fluoro-2′-deoxyguanosine has been reported to have potent anti-influenza virus activity in vitro ...
The carbocyclic analogues of (E)-5-(2-bromovinyl)-2'-deoxyuridine (C-BVDU) and (E)-5-(2-iodovinyl)-2...
The flavin-dependent thymidylate synthase X (ThyX), rare in eukaryotes and completely absent in huma...
Among the many prodrug approaches aimed at delivering nucleoside monophosphates into cells, the phos...
A series of novel dihydro-alkyloxy-benzyl-oxopyrimidine derivatives were synthesized and evaluated f...