Transport of proteins across membranes is essential during many stages of pathogen infection and colonization of human cells. Many Gram-negative pathogens use a Type 3 Secretion (T3S) system to inject proteins into the target cell during infection. Substantial genetic and biochemical evidence suggest that proteins are translocated across the host plasma membrane through a proteinaceous pore or translocon formed by two bacterial secreted proteins: the T3S translocators. Despite its key role in pathogenesis, virtually nothing is known about the assembly mechanism, structure, and composition of this critical transmembrane complex. To this end, a cell-free system for the structural and functional characterization of Pseudomonas aeruginosa T3S t...
International audiencePseudomonas aeruginosa efficiently intoxicates eukaryotic cells through the ac...
International audienceThe type III secretion system (T3SS) is a complex nanomachine employed by many...
Pseudomonas aeruginosa type III secretion apparatus exports and translocates four exotoxins into the...
Transport of proteins across membranes is essential during many stages of pathogen infection and col...
Type III secretion (T3S) system is deployed by a wide range of pathogens to manipulate host cell res...
Translocation of bacterial toxins or effectors into host cells using the type III secretion (T3S) sy...
AbstractPseudomonas aeruginosa is a major agent of hospital-acquired infections, and a pathogen of i...
International audienceType III secretion/translocation systems are essential actors in the pathogeni...
Type III secretion systems of Gram-negative pathogenic bacteria allow the injection of effector prot...
International audienceThe type III secretion system is a widespread apparatus used by pathogenic bac...
International audiencePseudomonas aeruginosa is a major agent of hospital-acquired infections, and a...
The pathogenesis of Pseudomonas aeruginosa (P.a) implies multiple virulence factors among which the ...
Pseudomonas aeruginosa, a Gram-negative pathogen utilizes a specialized set of Type III Secretion ...
La pathogénicité de P. aeruginosa (P. a) repose sur de nombreux facteurs de virulence dont le systèm...
International audiencePseudomonas aeruginosa efficiently intoxicates eukaryotic cells through the ac...
International audienceThe type III secretion system (T3SS) is a complex nanomachine employed by many...
Pseudomonas aeruginosa type III secretion apparatus exports and translocates four exotoxins into the...
Transport of proteins across membranes is essential during many stages of pathogen infection and col...
Type III secretion (T3S) system is deployed by a wide range of pathogens to manipulate host cell res...
Translocation of bacterial toxins or effectors into host cells using the type III secretion (T3S) sy...
AbstractPseudomonas aeruginosa is a major agent of hospital-acquired infections, and a pathogen of i...
International audienceType III secretion/translocation systems are essential actors in the pathogeni...
Type III secretion systems of Gram-negative pathogenic bacteria allow the injection of effector prot...
International audienceThe type III secretion system is a widespread apparatus used by pathogenic bac...
International audiencePseudomonas aeruginosa is a major agent of hospital-acquired infections, and a...
The pathogenesis of Pseudomonas aeruginosa (P.a) implies multiple virulence factors among which the ...
Pseudomonas aeruginosa, a Gram-negative pathogen utilizes a specialized set of Type III Secretion ...
La pathogénicité de P. aeruginosa (P. a) repose sur de nombreux facteurs de virulence dont le systèm...
International audiencePseudomonas aeruginosa efficiently intoxicates eukaryotic cells through the ac...
International audienceThe type III secretion system (T3SS) is a complex nanomachine employed by many...
Pseudomonas aeruginosa type III secretion apparatus exports and translocates four exotoxins into the...