To enable control of African swine fever (ASF) in Eastern and Southern Africa, prototype live vaccine candidates were generated by targeted gene deletions from a Kenyan genotype IX ASF virus (ASFV). It was attempted to delete known nonessential genes involved in virulence (encoding TK, dUTPase, CD2v, 9GL), possibly essential genes (p12, pA104R, ribonucleotide reductase), and genes with widely unknown functions (pK145R). Isolation of the desired virus recombinants by plaque assays or limiting dilutions on a wild boar lung cell line (WSL-HP) was facilitated by substitutive reporter gene insertions encoding fluorescent proteins (GFP, DsRed), or the human membrane protein CD4. The latter protein permitted enrichment of recombinant virus particl...
We describe the characterization of an African swine fever genotype IX virus (ASFV-Kenya-IX-1033), w...
Prevention and control of African swine fever virus (ASFV) in Europe, Asia, and Africa seem to be ex...
African swine fever (ASF) is a viral disease caused by African swine fever virus (ASFV), which leads...
African Swine Fever (ASF) is a highly contagious, viral disease of pigs caused by an Asfivirus. It c...
African swine fever (ASF) has become the major threat to the global swine industry. Lack of availabl...
African swine fever virus (ASFV) represents a serious threat to the global swine industry, and there...
African swine fever virus (ASFV) is the etiological agent of a contagious and fatal disease of domes...
African swine fever virus (ASFV) is the etiological agent of a contagious and fatal disease of domes...
African swine fever (ASF), is a viral disease of pigs and wild boar that is usually deadly. There ar...
African swine fever (ASF), occurring for many years, is at present the most significant viral diseas...
AbstractThe causative agent of ASF is a large deoxyvirus that has been assigned to Asfarviridae fami...
African swine fever (ASF) is an infectious Suidae disease caused by the ASF virus (ASFV). Adaptation...
African swine fever virus (ASFV) is the etiological agent of a highly lethal disease in both domesti...
African swine fever (ASF) is causing a pandemic affecting swine in a large geographical area of the ...
We describe the characterization of an African swine fever genotype IX virus (ASFV-Kenya-IX-1033), w...
We describe the characterization of an African swine fever genotype IX virus (ASFV-Kenya-IX-1033), w...
Prevention and control of African swine fever virus (ASFV) in Europe, Asia, and Africa seem to be ex...
African swine fever (ASF) is a viral disease caused by African swine fever virus (ASFV), which leads...
African Swine Fever (ASF) is a highly contagious, viral disease of pigs caused by an Asfivirus. It c...
African swine fever (ASF) has become the major threat to the global swine industry. Lack of availabl...
African swine fever virus (ASFV) represents a serious threat to the global swine industry, and there...
African swine fever virus (ASFV) is the etiological agent of a contagious and fatal disease of domes...
African swine fever virus (ASFV) is the etiological agent of a contagious and fatal disease of domes...
African swine fever (ASF), is a viral disease of pigs and wild boar that is usually deadly. There ar...
African swine fever (ASF), occurring for many years, is at present the most significant viral diseas...
AbstractThe causative agent of ASF is a large deoxyvirus that has been assigned to Asfarviridae fami...
African swine fever (ASF) is an infectious Suidae disease caused by the ASF virus (ASFV). Adaptation...
African swine fever virus (ASFV) is the etiological agent of a highly lethal disease in both domesti...
African swine fever (ASF) is causing a pandemic affecting swine in a large geographical area of the ...
We describe the characterization of an African swine fever genotype IX virus (ASFV-Kenya-IX-1033), w...
We describe the characterization of an African swine fever genotype IX virus (ASFV-Kenya-IX-1033), w...
Prevention and control of African swine fever virus (ASFV) in Europe, Asia, and Africa seem to be ex...
African swine fever (ASF) is a viral disease caused by African swine fever virus (ASFV), which leads...