Typ 1-Diabetes ist eine Autoimmunerkrankung, die zur Zerstörung der insulinproduzierenden Betazellen durch zytotoxische T-Lymphozyten führt. Es wird postuliert, dass der Prozeß durch verschiedene genetische Marker und Millieu-Cofaktoren beeinflusst wird. Es gibt Hinweise, dass Virusinfektionen einen T1D triggern können. Es wurden molekularbiologische Methoden zur molekularen Identifikation und Charakterisierung von Enterovirus RNA bzw. Adenovirus DNA etabliert. Es wurden signifikant erhöhte EV-RNA-Sequenzen in Autoantikörper-positiven Kindern und in Kindern mit neu diagnostizierten T1D nachgewiesen. Die Charakterisierung der Enterovirus-Amplicons zeigte eine hohe Homologie mit den Coxsackieviren B2, B4, B6 sowie mit ECHO 6. Für Adenovirus w...
Several health organizations have classified diabetes mellitus, a metabolic syndrome, as the epidemi...
Viruses are implicated in autoimmune destruction of pancreatic islet β cells, which results in insul...
This is the author accepted manuscript. The final version is available from Elsevier via the DOI in ...
Typ 1 diabetes (T1D) är en kronisk autoimmun sjukdom där insulinproduktionen försämrats på grund av ...
Autoreactive T-cell mediated destruction of insulin-containing beta-cells is the hallmark of Type 1 ...
Die Autoimmunerkrankung Typ-1-Diabetes ist durch einen Verlust der insulinproduzierenden Betazellen ...
Type I diabetes mellitus is a chronic autoimmune disease that results from the destruction of the in...
Enteroviren (EV) sind ein ätiologisches Agens von ZNS-Infektionen. Der schnelle Nachweis einer EV-In...
T1DM is an autoimmune disease in which beta-cells are selectively destroyed by the immune system. As...
Several epidemiological and clinical studies have indicated a possible role of Enterovirus (EV) infe...
Growing evidence has implicated members of the genus Enterovirus of the family Picornaviridae in the...
Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by insulin deficiency and result...
Beyond acute clinical conditions, the role of enteroviruses (EVs) in chronic human diseases has been...
Enteroviruses are RNA viruses known to cause several diseases e.g. hand, foot and mouth disease or a...
Enterovirusten ja tyypin 1 diabeteksen välinen yhteys eri maissa Tyypin 1 diabetes on autoimmuuni...
Several health organizations have classified diabetes mellitus, a metabolic syndrome, as the epidemi...
Viruses are implicated in autoimmune destruction of pancreatic islet β cells, which results in insul...
This is the author accepted manuscript. The final version is available from Elsevier via the DOI in ...
Typ 1 diabetes (T1D) är en kronisk autoimmun sjukdom där insulinproduktionen försämrats på grund av ...
Autoreactive T-cell mediated destruction of insulin-containing beta-cells is the hallmark of Type 1 ...
Die Autoimmunerkrankung Typ-1-Diabetes ist durch einen Verlust der insulinproduzierenden Betazellen ...
Type I diabetes mellitus is a chronic autoimmune disease that results from the destruction of the in...
Enteroviren (EV) sind ein ätiologisches Agens von ZNS-Infektionen. Der schnelle Nachweis einer EV-In...
T1DM is an autoimmune disease in which beta-cells are selectively destroyed by the immune system. As...
Several epidemiological and clinical studies have indicated a possible role of Enterovirus (EV) infe...
Growing evidence has implicated members of the genus Enterovirus of the family Picornaviridae in the...
Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by insulin deficiency and result...
Beyond acute clinical conditions, the role of enteroviruses (EVs) in chronic human diseases has been...
Enteroviruses are RNA viruses known to cause several diseases e.g. hand, foot and mouth disease or a...
Enterovirusten ja tyypin 1 diabeteksen välinen yhteys eri maissa Tyypin 1 diabetes on autoimmuuni...
Several health organizations have classified diabetes mellitus, a metabolic syndrome, as the epidemi...
Viruses are implicated in autoimmune destruction of pancreatic islet β cells, which results in insul...
This is the author accepted manuscript. The final version is available from Elsevier via the DOI in ...