Background: Muscle–bone deficits are common in pediatric Crohn’s disease; however, few studies have assessed long-term musculoskeletal outcomes in adults with childhood-onset Crohn’s disease. This study assessed the prevalence of musculoskeletal deficits in young adults with childhood-onset Crohn’s disease compared with healthy controls. Methods: High-resolution MRI and MR spectroscopy were used to assess bone microarchitecture, cortical geometry and muscle area, and adiposity at distal femur and bone marrow adiposity (BMA) at lumbar spine. Muscle function and biomarkers of the muscle-bone unit were also assessed. Results: Twenty-seven adults with Crohn’s disease with median (range) age 23.2 years (18.0, 36.1) and 27 age and sex-match...
Abstract Introduction: Crohn’s disease (CD) is an inflammatory bowel disease, marked by exacerbatio...
This is the author accepted manuscript. The final version is available from Elsevier via the DOI in ...
Background: Young individuals with Crohn disease (CD) are at risk of poor bone mineral density (BMD)...
Background: Muscle–bone deficits are common in pediatric Crohn’s disease; however, few studies have ...
Background: It is unclear whether Crohn’s disease (CD) is associated with skeletal disproportion in ...
Musculoskeletal deficits are among the most commonly reported extra-intestinal manifestations and co...
Musculoskeletal deficits are among the most commonly reported extra-intestinal manifestations and co...
Objectives: The aim of the study is to assess change in the muscle-bone unit in adolescents with C...
Background: Our research group has previously shown that low bone mineral density (BMD) is common in...
Background. Crohn’s disease (CD) is associated with multifactorial insult to the muscle-bone unit. T...
Background Young adults with childhood-onset inflammatory bowel disease (IBD) have increased risks o...
In Crohn\u27s disease (CD), skeletal muscle mass and function are reduced compared to healthy contro...
Metabolic bone disease is a frequent complication of Crohn’s disease (CD) with the pathogenesis of r...
Background: Patients with inflammatory bowel disease (IBD) often develop alterations in body composi...
Compromised skeletal status is a frequent finding in patients with Crohn’s disease (CD), leading to ...
Abstract Introduction: Crohn’s disease (CD) is an inflammatory bowel disease, marked by exacerbatio...
This is the author accepted manuscript. The final version is available from Elsevier via the DOI in ...
Background: Young individuals with Crohn disease (CD) are at risk of poor bone mineral density (BMD)...
Background: Muscle–bone deficits are common in pediatric Crohn’s disease; however, few studies have ...
Background: It is unclear whether Crohn’s disease (CD) is associated with skeletal disproportion in ...
Musculoskeletal deficits are among the most commonly reported extra-intestinal manifestations and co...
Musculoskeletal deficits are among the most commonly reported extra-intestinal manifestations and co...
Objectives: The aim of the study is to assess change in the muscle-bone unit in adolescents with C...
Background: Our research group has previously shown that low bone mineral density (BMD) is common in...
Background. Crohn’s disease (CD) is associated with multifactorial insult to the muscle-bone unit. T...
Background Young adults with childhood-onset inflammatory bowel disease (IBD) have increased risks o...
In Crohn\u27s disease (CD), skeletal muscle mass and function are reduced compared to healthy contro...
Metabolic bone disease is a frequent complication of Crohn’s disease (CD) with the pathogenesis of r...
Background: Patients with inflammatory bowel disease (IBD) often develop alterations in body composi...
Compromised skeletal status is a frequent finding in patients with Crohn’s disease (CD), leading to ...
Abstract Introduction: Crohn’s disease (CD) is an inflammatory bowel disease, marked by exacerbatio...
This is the author accepted manuscript. The final version is available from Elsevier via the DOI in ...
Background: Young individuals with Crohn disease (CD) are at risk of poor bone mineral density (BMD)...