Clinical and Histopathological Analysis on Features of 15 Cases with Urticarial Vasculitis

目的探讨荨麻疹性血管炎(UV)的临床和组织病理特征。方法分析15例UV患者的皮疹特点、实验室检查结果及组织病理学改变情况。结果男7例,女8例,男∶女=1∶1.14。平均年龄37.4岁,平均病程14.2月。皮疹以水肿性红斑(73.3%)和风团(60.0%)多见,全身不对称分布,伴瘙痒或疼痛。实验室检查异常以ESR加快(55.6%)和CRP升高(40.0%)多见,高免疫球蛋白血症和低补体血症者仅26.7%。组织病理显示所有患者均有程度不等的真皮浅层小静脉炎。结论UV是一种真皮浅层小静脉炎,但可累及皮下组织小动脉。Objective To analyze the clinical and histopathological features of urticarial vasculitis(UV).Methods Fifteen patients with urticarial vasculitis were examined of skin lesions,laboratory abnormalities and histopathological features.Results Among fifteen patients,seven were men and eight were women with a ratio of 1 to 1.14,the average age was 37.4 years,average duration was 14.2 months.The most common skin lesions were edematous erythema(73.3%)and wheals(60.0%),which were asymmetrically distributed on the whole body.The most common laboratory abnormalities were elevated ESR(55.6%)and CRP(40.0%).Hyperimmunoglobulinemia and hypocomplementemia were detected in only 26.7% of the patients.Histopathological examination revealed dermal veinulitis in all patients.Conclusion UV is a dermal veinulitis,in which subcutaneous arteries may be affected