HPTLC-densitometry: a step further for routine quality control of cranberry (Vaccinium macrocarpon) extracts

International audienceCranberry (Vaccinium macrocarpon) focused the interest of scientist for years now, due to assessed biological activities such as anti infectious, anti inflammatory or anti cancer activity. Anti infectious activity is linked to Proanthocyanidins A (P AC A), major P ACs in cranberry. To characterize P ACs content of cranberry extracts, official method is called BL-DMAC which is a global quantitation method. A new routine analytical method of P AC content will be presented here based on HPTLC -densitometry. This protocol allows selective quantitation of catechin, PAC-A2 and PAC B1 (both dimeric PACs) on one plate