Background: Non-specific interstitial pneumonia (NSIP) and fibrosing alveolitis associated with systemic sclerosis (FASSc) are diseases of unknown aetiology that are characterised by the accumulation of mononuclear cells, followed by the progressive deposition of collagen within the interstitium and subsequent destruction of lung airspace. Better understanding of mediators involved in fibrosis may be useful for early diagnosis and in clinical monitoring of disease progression. Objective: The aim of this study was to investigate the presence of two profibrotic markers, the vitronectin and the endothelin-1 (ET-1) in the airways of NSIP and FASSc patients. Methods: Ten NSIP (6 males, age 57 ± 2 years) and 15 FASSc (8 males, age 55 ± 4 years) p...
Sputum endothelin-1 is increased in cystic fibrosis and chronic obstructive pulmonary diseas
Vitronectin, a multifunctional glycoprotein, is involved in coagulation, inhibition of the forma-tio...
Background: beta-thymosins play roles in cytoskeleton rearrangement, angiogenesis, fibrosis and repa...
RATIONALE: Excessive pulmonary extracellular matrix (ECM) deposition leads to a progressive, permane...
The aim of this study was to determine the role of endothelin-1 (ET-1), a molecule involved in multi...
The aim of this study was to determine the role of endothelin-1 (ET-1), a molecule involved in multi...
Objectives. SSc is a systemic CTD characterized by fibrosis in skin and internal organs. Interstitia...
One recent line of cancer research is currently directed to the study of growth factors. Of increasi...
OBJECTIVE: Fibrosis is excessive scarring caused by the accumulation and contraction of extracellula...
Background Fibrotic Interstitial lung diseases (ILD) are a heterogeneous group of chronic lung disea...
Purpose: Human breath analysis is proposed with increasing frequency as a useful tool in clinical ap...
BACKGROUND:β-thymosins play roles in cytoskeleton rearrangement, angiogenesis, fibrosis and reparati...
Endothelin-1 (ET-1) is a vasoactive, mitogenic peptide that is variably increased in Bronchoalveolar...
BACKGROUND: Interstitial lung disease (ILD) complicates the course of systemic sclerosis (SSc), repr...
Fibronectin (FN) is known to promote fibroblast proliferation and attachment of collagen fibers at t...
Sputum endothelin-1 is increased in cystic fibrosis and chronic obstructive pulmonary diseas
Vitronectin, a multifunctional glycoprotein, is involved in coagulation, inhibition of the forma-tio...
Background: beta-thymosins play roles in cytoskeleton rearrangement, angiogenesis, fibrosis and repa...
RATIONALE: Excessive pulmonary extracellular matrix (ECM) deposition leads to a progressive, permane...
The aim of this study was to determine the role of endothelin-1 (ET-1), a molecule involved in multi...
The aim of this study was to determine the role of endothelin-1 (ET-1), a molecule involved in multi...
Objectives. SSc is a systemic CTD characterized by fibrosis in skin and internal organs. Interstitia...
One recent line of cancer research is currently directed to the study of growth factors. Of increasi...
OBJECTIVE: Fibrosis is excessive scarring caused by the accumulation and contraction of extracellula...
Background Fibrotic Interstitial lung diseases (ILD) are a heterogeneous group of chronic lung disea...
Purpose: Human breath analysis is proposed with increasing frequency as a useful tool in clinical ap...
BACKGROUND:β-thymosins play roles in cytoskeleton rearrangement, angiogenesis, fibrosis and reparati...
Endothelin-1 (ET-1) is a vasoactive, mitogenic peptide that is variably increased in Bronchoalveolar...
BACKGROUND: Interstitial lung disease (ILD) complicates the course of systemic sclerosis (SSc), repr...
Fibronectin (FN) is known to promote fibroblast proliferation and attachment of collagen fibers at t...
Sputum endothelin-1 is increased in cystic fibrosis and chronic obstructive pulmonary diseas
Vitronectin, a multifunctional glycoprotein, is involved in coagulation, inhibition of the forma-tio...
Background: beta-thymosins play roles in cytoskeleton rearrangement, angiogenesis, fibrosis and repa...