Acknowledgements The authors would like to acknowledge Dr David A. Blizard for his role in the development of the ideas that led to this study and feedback on the manuscript, Professor Helen Macdonald for valuable advice on study design, Dr Leslie R. Noble for help with the UK Biobank data, and Dr Joseph P. Gyekis for help genotyping cohort 2 mice. The authors would like to acknowledge funding from the University of Aberdeen for the Maxwell computer cluster, the Elphinstone and IMS studentship for AIHC; a Schweppe Foundation Career Development Award (AAP), and the NIH (NIAMS (AL: R01AR056280) and NIDA (AAP:R01DA021336, AAP:R21DA024845, AAP:T32MH020065, NMG:F31DA03635803), NIGMS (NMG:T32GM007197), NHGRI (MA:R01HG002899))Peer reviewedPostprin
Understanding how genetic variation shapes a complex trait relies on accurately quantifying both the...
PURPOSE: An osteopontin (OPN; SPP1) gene promoter polymorphism modifies disease severity in Duchenne...
The “replication crisis” has highlighted the apparent lack of replication across scientific fields. ...
Muscle bulk in adult healthy humans is highly variable even after height, age, and sex are accounted...
peer reviewedPhenome-wide association is a novel reverse genetic strategy to analyze genome-to-pheno...
We are grateful to Heather Lawson at Washington University in St. Louis for providing LG and SM geno...
The authors wish to acknowledge excellent technical assistance from A. Kurioka, L. Swadling, C. de L...
The authors wish to acknowledge technical assistance from: D. Godfrey, S. Lionikaite, V. Lionikaite,...
Purpose of Review To summarize the evidence from recent studies on the shared genetics between bone ...
There has been extensive discussion of the Replication Crisis in many fields, including genome-wid...
This dissertation is the culmination of my graduate studies in the laboratory of Jake Lusis at UCLA....
3 Human genome-wide association studies (GWAS) have identified thousands of loci associated with dis...
Understanding the genetic aetiology of loci associated with a disease is crucial for developing prev...
Abstract Title: Impact of Polymorphisms in PTK2 on Intrinsic Muscle Strength Primary Presenter Full ...
Lean body mass, consisting mostly of skeletal muscle, is important for healthy aging. We performed a...
Understanding how genetic variation shapes a complex trait relies on accurately quantifying both the...
PURPOSE: An osteopontin (OPN; SPP1) gene promoter polymorphism modifies disease severity in Duchenne...
The “replication crisis” has highlighted the apparent lack of replication across scientific fields. ...
Muscle bulk in adult healthy humans is highly variable even after height, age, and sex are accounted...
peer reviewedPhenome-wide association is a novel reverse genetic strategy to analyze genome-to-pheno...
We are grateful to Heather Lawson at Washington University in St. Louis for providing LG and SM geno...
The authors wish to acknowledge excellent technical assistance from A. Kurioka, L. Swadling, C. de L...
The authors wish to acknowledge technical assistance from: D. Godfrey, S. Lionikaite, V. Lionikaite,...
Purpose of Review To summarize the evidence from recent studies on the shared genetics between bone ...
There has been extensive discussion of the Replication Crisis in many fields, including genome-wid...
This dissertation is the culmination of my graduate studies in the laboratory of Jake Lusis at UCLA....
3 Human genome-wide association studies (GWAS) have identified thousands of loci associated with dis...
Understanding the genetic aetiology of loci associated with a disease is crucial for developing prev...
Abstract Title: Impact of Polymorphisms in PTK2 on Intrinsic Muscle Strength Primary Presenter Full ...
Lean body mass, consisting mostly of skeletal muscle, is important for healthy aging. We performed a...
Understanding how genetic variation shapes a complex trait relies on accurately quantifying both the...
PURPOSE: An osteopontin (OPN; SPP1) gene promoter polymorphism modifies disease severity in Duchenne...
The “replication crisis” has highlighted the apparent lack of replication across scientific fields. ...