A model of a population is constructed by bringing together individual model organisms (cells) which have explicit internal dynamics. An attempt is made to preserve analyzability of the relatively complex model by describing the nonlinear dynamics of each cell by a set of piece-wise linear equations. In the simplest case of three linear pieces, a population with inherent oscillations in the number of cells as a function of time is obtained. A proposal is made to approximate realistic internal dynamics of selected biological features by introducing the appropriate number of linear patches, and to simulate realistic populations in this way. Another extension of the model, the description of interactions between cells through released metaboli...
Computationally complex systems models are needed to advance research and implement policy in theore...
Abstract: We consider the dynamics of a biological community described by two ordinary non...
The paper provides a qualitative analysis of M.S. Vinogradova's nonlinear model for dynamics of the ...
We investigated a cell-population modelling technique in which the population is constructed from an...
International audienceThe paper is devoted to hybrid discrete-continuous models of cell populations ...
International audienceThe paper is devoted to hybrid discrete-continuous models of cell populations ...
International audienceThe paper is devoted to hybrid discrete-continuous models of cell populations ...
A mathematical model is proposed for describing the population dynamics of cellular clusters on the ...
We study the mathematical properties of a general model of cell division structured with several int...
Biological systems are intrinsically heterogeneous and, consequently, their mathematical description...
We introduce a model for describing the dynamics of large numbers of interacting cells. The fundamen...
We introduce a model for describing the dynamics of large numbers of interacting cells. The fundamen...
The processes taking place inside the living cell are now understood to the point where predictive c...
Computationally complex systems models are needed to advance research and implement policy in theore...
The processes taking place inside the living cell are now understood to the point where predictive c...
Computationally complex systems models are needed to advance research and implement policy in theore...
Abstract: We consider the dynamics of a biological community described by two ordinary non...
The paper provides a qualitative analysis of M.S. Vinogradova's nonlinear model for dynamics of the ...
We investigated a cell-population modelling technique in which the population is constructed from an...
International audienceThe paper is devoted to hybrid discrete-continuous models of cell populations ...
International audienceThe paper is devoted to hybrid discrete-continuous models of cell populations ...
International audienceThe paper is devoted to hybrid discrete-continuous models of cell populations ...
A mathematical model is proposed for describing the population dynamics of cellular clusters on the ...
We study the mathematical properties of a general model of cell division structured with several int...
Biological systems are intrinsically heterogeneous and, consequently, their mathematical description...
We introduce a model for describing the dynamics of large numbers of interacting cells. The fundamen...
We introduce a model for describing the dynamics of large numbers of interacting cells. The fundamen...
The processes taking place inside the living cell are now understood to the point where predictive c...
Computationally complex systems models are needed to advance research and implement policy in theore...
The processes taking place inside the living cell are now understood to the point where predictive c...
Computationally complex systems models are needed to advance research and implement policy in theore...
Abstract: We consider the dynamics of a biological community described by two ordinary non...
The paper provides a qualitative analysis of M.S. Vinogradova's nonlinear model for dynamics of the ...