Carotis intima media thickness in female patiens with subclinical hypothyroidism [Subklinik hipotiroidili kadin hastalarda karotis intima media kalinli?i]

Objective: Recent studies have shown that subclinical hypothyroidism (SCH) has similar cardiovascular risks with clinical hypothyroidism (CH). We evaluated carotis intima media thickness (CIMT)-indicator of early changes in atherosclerotic process- in female patients, who have either CH or SCH, with similar age and demographic features. Materials and Methods: In this study, we included 81 female patients admitted to internal medicine and endocrinology outpatient clinic, diagnosed with CH (30) or SCH (51) according to their laboratory findings and who have not previously received treatment and 38 healthy women. BMI (body mass index), sistolic and diastolic blood pressure, triglycerides (TG), total cholesterol (TC), LDL cholesterol (LDL-C), HDL cholesterol (HDL-C), vitamin B-12, folate, homocysteine, high-sensitive C-reactive protein (Hs CRP), and CIMT were measured in all participants. Results: There was not a statistical difference between the groups in TG, TC, HDL-C, LDL-C, vitamin B-12, and folate levels (p>0.05). On the other hand, SCH and CH groups differed statistically significantly from the control group for Hs CRP (p=0.011), homocysteine (p