İnme hastalarinda lezyon lokalizasyonu ve depresyon i?lişkisi

Objective: There is a need for more systematical and wide-spread studies because of the methodological problems in scientific studies discussing the relationship between depression and localization. Method: Forty patients with first stroke and meeting the inclusion criteria were examined prospectively during 6 month study period. The diagnosis of depression was made by using DSM-IV diagnostic tool and the patients were followed by using Hamilton Depression Scale by a specialist on psychiatry. The findings got from the cranial imaging were evaluated and classified as lesions located in anterior, posterior or medial part / in the left or right hemisphere by using a standard method. The differences of lesions between the patients who developed the depression and the patients without depression were evaluated during follow-up period. Results: The study population consisted of 40 patients - 13 women (32.5%) and 27 men (67.5%). The relationship between depression and lesion localization whether right or left hemisphere was not significant , but the relationship between depression and anteriorly located lesions was statistically significant. Conclusion: Additional to previous structural imaging studies, neuropsychological examinations and functional studies reporting a relation between development of depression and lesions located on the left side and anterior part, our results show that there could be a relationship between depression and anterior lesions in the first ever stroke patients