Proactive priming before the next pandemic could induce immune memory responses to novel influenza antigens. In an open-label study, we analyzed B cell memory and antibody responses of 54 adults who received 2 7.5-μg doses of MF59-adjuvanted A/Vietnam/1194/2004 clade 1 (H5N1) vaccine. Twenty-four subjects had been previously primed with MF59-adjuvanted or plain clade 0-like A/duck/Singapore/1997 (H5N3) vaccine during 1999–2001. The prevaccination frequency of circulating memory B cells reactive to A/Vietnam/1194/2004 was low in both primed and unprimed individuals. However, at day 21 after boosting, MF59-adjuvanted primed subjects displayed a higher frequency of H5N1-specific memory B cells than plain-primed or unprimed subjects. The immune...
Influenza vaccination is a common approach to prevent seasonal and pandemic influenza. Pre-existing ...
Influenza vaccination is a common approach to prevent seasonal and pandemic influenza. Pre-existing ...
Neutralising antibodies and antigen-specific B cells are important for protection against influenza ...
Proactive priming before the next pandemic could induce immune memory responses to novel influenza a...
Background: Priming against strains with pandemic potential, such as H5N1, with vaccines that induce...
Protective antibody responses to a single dose of 2009 pandemic vaccines have been observed in the m...
Over last years, a novel strategy for vaccination of people against potentially pandemic influenza A...
In an open label clinical study (2007), MF59-adjuvanted hemagglutinin (HA) vaccine from H5N1-A/Vietn...
Background: Pathogenic avian influenza virus (H5N1) has the potential to cause a major global pandem...
Pathogenic avian influenza virus (H5N1) has the potential to cause a major global pandemic in humans...
BACKGROUND: Pathogenic avian influenza virus (H5N1) has the potential to cause a major global pande...
Vaccine-induced memory B cell responses to evolving viruses like influenza A involve activation of p...
Novel strategies are required to provide rapid vaccine coverage in the event of an influenza pandemi...
UNLABELLED: Avian influenza continues to circulate and remains a global health threat not least beca...
Avian influenza continues to circulate and remains a global health threat not least because of the a...
Influenza vaccination is a common approach to prevent seasonal and pandemic influenza. Pre-existing ...
Influenza vaccination is a common approach to prevent seasonal and pandemic influenza. Pre-existing ...
Neutralising antibodies and antigen-specific B cells are important for protection against influenza ...
Proactive priming before the next pandemic could induce immune memory responses to novel influenza a...
Background: Priming against strains with pandemic potential, such as H5N1, with vaccines that induce...
Protective antibody responses to a single dose of 2009 pandemic vaccines have been observed in the m...
Over last years, a novel strategy for vaccination of people against potentially pandemic influenza A...
In an open label clinical study (2007), MF59-adjuvanted hemagglutinin (HA) vaccine from H5N1-A/Vietn...
Background: Pathogenic avian influenza virus (H5N1) has the potential to cause a major global pandem...
Pathogenic avian influenza virus (H5N1) has the potential to cause a major global pandemic in humans...
BACKGROUND: Pathogenic avian influenza virus (H5N1) has the potential to cause a major global pande...
Vaccine-induced memory B cell responses to evolving viruses like influenza A involve activation of p...
Novel strategies are required to provide rapid vaccine coverage in the event of an influenza pandemi...
UNLABELLED: Avian influenza continues to circulate and remains a global health threat not least beca...
Avian influenza continues to circulate and remains a global health threat not least because of the a...
Influenza vaccination is a common approach to prevent seasonal and pandemic influenza. Pre-existing ...
Influenza vaccination is a common approach to prevent seasonal and pandemic influenza. Pre-existing ...
Neutralising antibodies and antigen-specific B cells are important for protection against influenza ...