This thesis contains three essays on dependence modelling with high dimension vine copulas and its applications in credit portfolio risk, asset allocation and international financial contagion. In the first essay, we demonstrate the superiority of vine copulas over multivariate Gaussian copula when modelling the dependence structure of a credit portfolio risk factors. We introduce the vine copulas to modelling the dependence structure of multi risk factors log returns in the combined framework of both threshold model and mixture model credit risk modelling. The second essay studies asset allocation decisions in the presence of regime switching on asset allocation with alternative investments. We find evidence that two regimes, characterized...