Perturbed information processing in the amygdala has been implicated in developmentally originating neuropsychiatric disorders. However, little is known on the mechanisms that guide formation and refinement of intrinsic connections between amygdaloid nuclei. We demonstrate that in rodents the glutamatergic connection from basolateral to central amygdala (BLA-CeA) develops rapidly during the first 10 postnatal days, before external inputs underlying amygdala-dependent behaviors emerge. During this restricted period of synaptic development, kainate-type of ionotropic glutamate receptors (KARs) are highly expressed in the BLA and tonically activated to regulate glutamate release via a G-protein-dependent mechanism. Genetic manipulation of this...
International audienceIn the neonatal hippocampus, the activity of interneurons shapes early network...
The significance for CNS function of glutamate-gated cation channels that exhibit high-affinity kain...
At the onset of a period of intense synaptic refinement initiated by synchronized eye opening (EO), ...
Kainate receptors (KARs) are highly expressed in the immature brain and have unique developmentally ...
Early life stress (ELS) is a well-characterized risk factor for mood and anxiety disorders. GABAergi...
Kainic acid receptor (KA-R) subunits are differentially expressed during brain development, and they...
Kainate type glutamate receptors (KARs) are strongly expressed in GABAergic interneurons and have th...
Summary: Both inhibitory and excitatory neurotransmitter receptors can influence maturation and surv...
Kainate (KA) receptors are a family of ionotropic glutamate receptors, which mediate the excitatory ...
SummaryEarly in development, excitatory synapses transmit with low efficacy, one mechanism for which...
NETO2 is an auxiliary subunit for kainate-type glutamate receptors that mediate normal cued fear exp...
Kainate receptors are members of the glutamate receptor family that regulate synaptic function in th...
Neurotransmitters and their receptors are key molecules of signal transduction and subject to variou...
Presynaptic kainate (KA) receptors (KARs) modulate GABA and glutamate release in the central nervous...
AbstractPrevious studies have shown that pharmacological activation of presynaptic kainate receptors...
International audienceIn the neonatal hippocampus, the activity of interneurons shapes early network...
The significance for CNS function of glutamate-gated cation channels that exhibit high-affinity kain...
At the onset of a period of intense synaptic refinement initiated by synchronized eye opening (EO), ...
Kainate receptors (KARs) are highly expressed in the immature brain and have unique developmentally ...
Early life stress (ELS) is a well-characterized risk factor for mood and anxiety disorders. GABAergi...
Kainic acid receptor (KA-R) subunits are differentially expressed during brain development, and they...
Kainate type glutamate receptors (KARs) are strongly expressed in GABAergic interneurons and have th...
Summary: Both inhibitory and excitatory neurotransmitter receptors can influence maturation and surv...
Kainate (KA) receptors are a family of ionotropic glutamate receptors, which mediate the excitatory ...
SummaryEarly in development, excitatory synapses transmit with low efficacy, one mechanism for which...
NETO2 is an auxiliary subunit for kainate-type glutamate receptors that mediate normal cued fear exp...
Kainate receptors are members of the glutamate receptor family that regulate synaptic function in th...
Neurotransmitters and their receptors are key molecules of signal transduction and subject to variou...
Presynaptic kainate (KA) receptors (KARs) modulate GABA and glutamate release in the central nervous...
AbstractPrevious studies have shown that pharmacological activation of presynaptic kainate receptors...
International audienceIn the neonatal hippocampus, the activity of interneurons shapes early network...
The significance for CNS function of glutamate-gated cation channels that exhibit high-affinity kain...
At the onset of a period of intense synaptic refinement initiated by synchronized eye opening (EO), ...