The afferent and efferent arterioles regulate the inflow and outflow resistance of the glomerulus, acting in concert to control the glomerular capillary pressure and glomerular filtration rate. The myocytes of these two vessels are remarkably different, especially regarding electromechanical coupling. This study investigated the expression and function of inward rectifier K+ channels in these two vessels using perfused hydronephrotic rat kidneys and arterioles and myocytes isolated from normal rat kidneys. In afferent arterioles pre-constricted with angiotensin II, elevating [K+]0 from 5 to 15 mmol/L induced hyperpolarization (–27 ± 2 to –41 ± 3 mV) and vasodilation (6.6 ± 0.9 to 13.1 ± 0.6 µm). This manipulation also attenuated angiotens...
Transient receptor potential channels in rat renal microcirculation: Actions of angiotensin II.Backg...
The present study was designed to elucidate whether the conduction of vasomotor responses mediated b...
Objective- Inward rectifying K+ (KIR) channels are present in cerebral arterial smooth muscle and en...
The afferent and efferent arterioles regulate the inflow and outflow resistance of the glomerulus, a...
Aims: We investigated the role of the inward rectifier K+ channel (KIR) in the renal interlobular ar...
Aims: We investigated the role of the inward rectifier K+ channel (KIR) in the renal interlobular ar...
Aims: We investigated the role of the inward rectifier K+ channel (KIR) in the renal interlobular ar...
Strong inward rectifying K+ (KIR) channels have been observed in vascular smooth muscle and can disp...
Transient receptor potential channels in rat renal microcirculation: Actions of angiotensin II.Backg...
K(+) channels play indispensable roles in establishing the membrane potential and in regulating the ...
The distribution of functionally active, inwardly rectifying K (K(IR)) channels was investigated in ...
The distribution of functionally active, inwardly rectifying K (K(IR)) channels was investigated in ...
Copyright © 2003 S. Karger AG, BaselThe distribution of functionally active, inwardly rectifying K (...
A narrow segment of the efferent arteriole controls efferent resistance in the hydronephrotic rat ki...
A narrow segment of the efferent arteriole controls efferent resistance in the hydronephrotic rat ki...
Transient receptor potential channels in rat renal microcirculation: Actions of angiotensin II.Backg...
The present study was designed to elucidate whether the conduction of vasomotor responses mediated b...
Objective- Inward rectifying K+ (KIR) channels are present in cerebral arterial smooth muscle and en...
The afferent and efferent arterioles regulate the inflow and outflow resistance of the glomerulus, a...
Aims: We investigated the role of the inward rectifier K+ channel (KIR) in the renal interlobular ar...
Aims: We investigated the role of the inward rectifier K+ channel (KIR) in the renal interlobular ar...
Aims: We investigated the role of the inward rectifier K+ channel (KIR) in the renal interlobular ar...
Strong inward rectifying K+ (KIR) channels have been observed in vascular smooth muscle and can disp...
Transient receptor potential channels in rat renal microcirculation: Actions of angiotensin II.Backg...
K(+) channels play indispensable roles in establishing the membrane potential and in regulating the ...
The distribution of functionally active, inwardly rectifying K (K(IR)) channels was investigated in ...
The distribution of functionally active, inwardly rectifying K (K(IR)) channels was investigated in ...
Copyright © 2003 S. Karger AG, BaselThe distribution of functionally active, inwardly rectifying K (...
A narrow segment of the efferent arteriole controls efferent resistance in the hydronephrotic rat ki...
A narrow segment of the efferent arteriole controls efferent resistance in the hydronephrotic rat ki...
Transient receptor potential channels in rat renal microcirculation: Actions of angiotensin II.Backg...
The present study was designed to elucidate whether the conduction of vasomotor responses mediated b...
Objective- Inward rectifying K+ (KIR) channels are present in cerebral arterial smooth muscle and en...